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Your translated search: succinate = 919 reactions were found.
State Icon Reaction EC-Number Conf. maximal confidence score from EnzymeDetector PW
H2O + S-succinylglutathione <=> H+ + succinate + glutathione 3.1.2.13 S-succinylglutathione hydrolase
3.1.2.6 hydroxyacylglutathione hydrolase


succinyl-CoA + H2O <=> H+ + succinate + CoA 3.1.2.1 acetyl-CoA hydrolase
3.1.2.2 palmitoyl-CoA hydrolase
3.1.2.3 succinyl-CoA hydrolase
6.2.1.4 succinate---CoA ligase (GDP-forming)




H2O + N-succinyl-LL-2,6-diaminoheptanedioate <=> LL-2,6-Diaminoheptanedioate + succinate 3.5.1.18 succinyl-diaminopimelate desuccinylase

BMK
taurine + 2-oxoglutarate + O2 <=> H+ + sulfite + aminoacetaldehyde + succinate + CO2 1.14.11.17 taurine dioxygenase

BMK
phytanoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxyphytanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

(2R,3S,4S)-leucoanthocyanidin + 2-oxoglutarate + O2 + H+ <=> anthocyanidin + succinate + CO2 + H2O 1.14.20.4 anthocyanidin synthase

succinate_semialdehyde + NADP+ + H2O <=> NADPH + succinate + H+ 1.1.1.21 aldose reductase
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)





BMK
succinate_semialdehyde + NAD+ + H2O <=> NADH + succinate + H+ 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.21 glycolaldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase








BMK
succinamate + H2O <=> succinate + NH3 3.5.1.1 asparaginase
3.5.1.131 1-carboxybiuret hydrolase
3.5.1.3 omega-amidase
3.5.1.38 glutamin-(asparagin-)ase
3.5.1.4 amidase





isocitrate <=> glyoxylate + succinate 4.1.3.1 isocitrate lyase

BMK
succinate + NAD+ <=> fumarate + NADH + H+ 1.3.1.6 fumarate reductase (NADH)

K
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate <=> succinate + pyruvate 4.1.3.1 isocitrate lyase
4.1.3.30 methylisocitrate lyase


BMK
(2S)-flavanone + 2-oxoglutarate + O2 <=> (2R,3R)-dihydroflavonol + succinate + CO2 1.14.11.9 flavanone 3-dioxygenase

Procollagen_L-proline + 2-oxoglutarate + O2 <=> procollagen_trans-3-hydroxy-L-proline + succinate + CO2 1.14.11.7 procollagen-proline 3-dioxygenase

M
thymine + 2-oxoglutarate + O2 <=> 5-Hydroxymethyluracil + succinate + CO2 1.14.11.6 thymine dioxygenase

2''-deoxyuridine + 2-oxoglutarate + O2 <=> uridine + succinate + CO2 1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase

gibberellin_a20 + 2-oxoglutarate + O2 <=> gibberellin_1 + succinate + CO2 1.14.11.15 gibberellin 3beta-dioxygenase

MK
6beta-hydroxyhyoscyamine + 2-oxoglutarate + O2 <=> H+ + Scopolamine + succinate + CO2 + H2O 1.14.11.11 hyoscyamine (6S)-dioxygenase
1.14.20.13 6beta-hydroxyhyoscyamine epoxidase


MK
gibberellin_1 + 2-oxoglutarate + O2 <=> 2beta-hydroxygibberellin_1 + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

MK
L-hyoscyamine + 2-oxoglutarate + O2 <=> 6beta-hydroxyhyoscyamine + succinate + CO2 1.14.11.11 hyoscyamine (6S)-dioxygenase

MK
2''-deoxyuridine + 2-oxoglutarate + O2 <=> 2-deoxyribonolactone + succinate + CO2 + Uracil 1.14.11.10 pyrimidine-deoxynucleoside 1'-dioxygenase

gamma-butyrobetaine + 2-oxoglutarate + O2 <=> L-carnitine + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

MK
deacetoxyvindoline + 2-oxoglutarate + O2 <=> deacetylvindoline + succinate + CO2 1.14.11.20 deacetoxyvindoline 4-hydroxylase

MK
Penicillin_N + 2-oxoglutarate + O2 <=> deacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

MK
succinyl-CoA + (R)-2-benzylsuccinate <=> succinate + (R)-2-benzylsuccinyl-CoA 2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase

MK
O-succinyl-L-homoserine + L-cysteine <=> L-cystathionine + succinate + H+ 2.5.1.48 cystathionine gamma-synthase

BMK
deoxyamidinoproclavaminate + 2-oxoglutarate + O2 <=> amidinoproclavaminate + succinate + CO2 1.14.11.21 clavaminate synthase

MK
proclavaminate + 2-oxoglutarate + O2 <=> dihydroclavaminate + CO2 + H2O + succinate 1.14.11.21 clavaminate synthase

MK
dihydroclavaminate + 2-oxoglutarate + O2 <=> clavaminate + CO2 + H2O + succinate 1.14.11.21 clavaminate synthase

MK
succinyl-CoA + 3-hydroxy-3-methylglutarate <=> succinate + (S)-3-hydroxy-3-methylglutaryl-CoA 2.8.3.13 succinate---hydroxymethylglutarate CoA-transferase

succinyl-CoA + oxalate <=> succinate + oxalyl-CoA 2.8.3.2 oxalate CoA-transferase

MK
succinyl-CoA + a_3-oxo_acid <=> succinate + 3-oxoacyl-CoA 2.8.3.5 3-oxoacid CoA-transferase

succinyl-CoA + 3-oxoadipate <=> succinate + 3-oxoadipyl-CoA 2.8.3.6 3-oxoadipate CoA-transferase

BMK
flavanone + 2-oxoglutarate + O2 <=> flavone + succinate + CO2 + H2O 1.14.20.5 flavone synthase I

deacetoxycephalosporin_C + 2-oxoglutarate + O2 <=> deacetylcephalosporin_C + succinate + CO2 1.14.11.26 deacetoxycephalosporin-C hydroxylase
1.14.20.1 deacetoxycephalosporin-C synthase


MK
2''-deoxymugineate + 2-oxoglutarate + O2 <=> H+ + mugineic_acid + succinate + CO2 1.14.11.24 2'-deoxymugineic-acid 2'-dioxygenase

M
mugineic_acid + 2-oxoglutarate + O2 <=> 3-epihydroxymugineic_acid + succinate + CO2 1.14.11.25 mugineic-acid 3-dioxygenase

M
2''-deoxymugineate + 2-oxoglutarate + O2 <=> 3-epihydroxy-2''-deoxymugineate + succinate + CO2 + H+ 1.14.11.25 mugineic-acid 3-dioxygenase

M
histone_H3_N6,N6-dimethyl-L-lysine36 + 2-oxoglutarate + O2 <=> histone_H3(K36) + succinate + formaldehyde + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase
1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase



histone_H3_N6,N6-dimethyl-L-lysine36 + 2-oxoglutarate + O2 <=> [histone_H3]_N6-methyl-L-lysine-36 + formaldehyde + succinate + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase



L-proline + 2-oxoglutarate + O2 <=> cis-3-hydroxy-L-proline + succinate + CO2 1.14.11.28 proline 3-hydroxylase

[histone_H3]_N6,N6,N6-trimethyl-L-lysine-9 + 2-oxoglutarate + O2 <=> [histone_H3]_N6-methyl-L-lysine-9 + formaldehyde + succinate + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

[histone_H3]_N6,N6,N6-trimethyl-L-lysine-4 + 2-oxoglutarate + O2 <=> histone_H3(K4) + succinate + formaldehyde + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase



L-proline + 2-oxoglutarate + O2 <=> cis-4-hydroxyproline + succinate + CO2 1.14.11.56 L-proline cis-4-hydroxylase

thebaine + 2-oxoglutarate + O2 <=> neopinone + formaldehyde + succinate + CO2 1.14.11.31 thebaine 6-O-demethylase

MK
codeine + 2-oxoglutarate + O2 <=> morphine + formaldehyde + succinate + CO2 1.14.11.32 codeine 3-O-demethylase

MK
L-dihydroorotate + fumarate <=> Orotate + succinate 1.3.98.1 dihydroorotate dehydrogenase (fumarate)

MK
(2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O <=> (2Z)-2-hydroxypenta-2,4-dienoate + succinate + H+ 3.7.1.14 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase

M
L-arginine + 2-oxoglutarate + O2 <=> L-pyrroline-5-carboxylate + guanidine + succinate + CO2 + H2O + H+ 1.14.20.7 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)

M
DIBOA-glucoside + O2 + 2-oxoglutarate <=> (2R)-4,7-dihydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl_beta-D-glucopyranoside + succinate + CO2 1.14.11.59 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase

MK
(+/-)-1-deoxypentalenic_acid + 2-oxoglutarate + O2 <=> 1-deoxy-11beta-hydroxypentalenic_acid + succinate + CO2 1.14.11.35 1-deoxypentalenic acid 11beta-hydroxylase

MK
pentalenolactone_D + 2-oxoglutarate + O2 <=> pentalenolactone_F + succinate + CO2 + H2O 1.14.11.36 pentalenolactone F synthase

K
pentalenolactone_D + O2 + 2-oxoglutarate <=> pentalenolactone_E + succinate + CO2 + H2O 1.14.11.36 pentalenolactone F synthase

M
pentalenolactone_E + O2 + 2-oxoglutarate <=> pentalenolactone_F + succinate + CO2 1.14.11
1.14.11.36 pentalenolactone F synthase


M
kanamycin_B + 2-oxoglutarate + O2 <=> 2''-dehydrokanamycin_A + succinate + NH3 + CO2 1.14.11.37 kanamycin B dioxygenase

MK
succinyl-CoA + acetate <=> succinate + acetyl-CoA 2.8.3.1 propionate CoA-transferase
2.8.3.18 succinyl-CoA:acetate CoA-transferase
2.8.3.8 acetate CoA-transferase



BMK
2-oxoglutarate + L-asparagine + O2 <=> (2S,3S)-3-hydroxyasparagine + succinate + CO2 1.14.11.39 L-asparagine hydroxylase

L-enduracididine + 2-oxoglutarate + O2 <=> (3S)-3-hydroxy-L-enduracididine + succinate + CO2 1.14.11.40 enduracididine beta-hydroxylase

L-arginine + 2-oxoglutarate + O2 <=> (2S,3S)-3-hydroxyarginine + succinate + CO2 1.14.11.41 L-arginine hydroxylase

BM
(R)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 <=> 4-chloro-2-methylphenol + pyruvate + succinate + CO2 1.14.11.43 (S)-dichlorprop dioxygenase (2-oxoglutarate)
1.14.11.44 (R)-dichlorprop dioxygenase (2-oxoglutarate)


(R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 <=> 2,4-Dichlorophenol + pyruvate + succinate + CO2 1.14.11.44 (R)-dichlorprop dioxygenase (2-oxoglutarate)

(S)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 <=> 4-chloro-2-methylphenol + pyruvate + succinate + CO2 1.14.11.43 (S)-dichlorprop dioxygenase (2-oxoglutarate)

(S)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 <=> 2,4-Dichlorophenol + pyruvate + succinate + CO2 1.14.11.43 (S)-dichlorprop dioxygenase (2-oxoglutarate)

(3S,5S)-carbapenam_3-carboxylate + 2-oxoglutarate + O2 <=> (5R)-carbapen-2-em-3-carboxylate + succinate + CO2 + H2O 1.14.20
1.14.20.3 (5R)-carbapenem-3-carboxylate synthase


BMK
fumarate + coenzyme_M + coenzyme_B <=> succinate + CoM-S-S-CoB 1.3.4.1 fumarate reductase (CoM/CoB)

K
succinyl-CoA + (R)-citramalate <=> succinate + (3R)-citramalyl-CoA 2.8.3.20 succinyl-CoA---D-citramalate CoA-transferase

succinyl-CoA + D-malate <=> succinate + (R)-malyl-CoA 2.8.3.18 succinyl-CoA:acetate CoA-transferase
2.8.3.20 succinyl-CoA---D-citramalate CoA-transferase


succinyl-CoA + (S)-malate <=> succinate + (3S)-3-carboxy-3-hydroxypropanoyl-CoA 2.8.3.18 succinyl-CoA:acetate CoA-transferase
2.8.3.22 succinyl-CoA---L-malate CoA-transferase


MK
succinyl-CoA + (+)-citramalate <=> (3S)-citramalyl-CoA + succinate 2.8.3.22 succinyl-CoA---L-malate CoA-transferase

K
L-isoleucine + 2-oxoglutarate + O2 <=> (4S)-4-hydroxy-L-isoleucine + succinate + CO2 1.14.11.45 L-isoleucine 4-hydroxylase

xanthine + 2-oxoglutarate + O2 <=> Urate + succinate + CO2 1.14.11.48 xanthine dioxygenase

UMP + 2-oxoglutarate + O2 <=> 5''-dehydrouridine + succinate + CO2 + phosphate 1.14.11.49 uridine-5'-phosphate dioxygenase

(-)-yatein + 2-oxoglutarate + O2 <=> (-)-deoxypodophyllotoxin + succinate + CO2 + H2O 1.14.20.8 (-)-deoxypodophyllotoxin synthase

MK
N6-methyladenine_in_DNA + 2-oxoglutarate + O2 <=> adenine_in_DNA + formaldehyde + succinate + CO2 1.14.11.51 DNA N6-methyladenine demethylase

validamycin_A + 2-oxoglutarate + O2 <=> validamycin_B + succinate + CO2 1.14.11.52 validamycin A dioxygenase

MK
N6-methyladenine_in_tRNA + 2-oxoglutarate + O2 <=> adenine_in_mRNA + formaldehyde + succinate + CO2 1.14.11.53 mRNA N6-methyladenine demethylase

N1-methyladenine_in_mRNA + 2-oxoglutarate + O2 <=> adenine_in_mRNA + formaldehyde + succinate + CO2 1.14.11.54 mRNA N1-methyladenine demethylase

(2R,3S,4S)-leucoanthocyanidin + 2-oxoglutarate + O2 <=> a_(4S)-_2,3-dehydroflavan-3,4-diol + succinate + CO2 + H2O 1.14.20.4 anthocyanidin synthase

M
L-ectoine + 2-oxoglutarate + O2 <=> 5-hydroxyectoine + succinate + CO2 1.14.11.55 ectoine hydroxylase

K
L-proline + 2-oxoglutarate + O2 <=> trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase
1.14.11.57 L-proline trans-4-hydroxylase


K
an_ornithine_lipid + 2-oxoglutarate + O2 <=> a_2-hydroxyornithine_lipid + succinate + CO2 1.14.11.58 ornithine lipid ester-linked acyl 2-hydroxylase

(2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 <=> (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate + succinate + CO2 + H2O 1.14.20.9 L-tyrosine isonitrile desaturase

M
(2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H+ <=> 4-[(E)-2-isocyanoethenyl]phenol + succinate + CO2 + H2O 1.14.20.10 L-tyrosine isonitrile desaturase/decarboxylase

M
(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H+ <=> 3-[(Z)-2-isocyanoethenyl]-1H-indole + succinate + CO2 + H2O 1.14.20.11 3-[(Z)-2-isocyanoethenyl]-1H-indole synthase

M
(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H+ <=> 3-[(E)-2-isocyanoethenyl]-1H-indole + succinate + CO2 + H2O 1.14.20.12 3-[(E)-2-isocyanoethenyl]-1H-indole synthase

M
hapalindole_U + 2-oxoglutarate + O2 + Cl- + H+ <=> hapalindole_G + succinate + CO2 + H2O 1.14.20.14 hapalindole-type alkaloid chlorinase

12-epi-fischerindole_U + 2-oxoglutarate + O2 + Cl- + H+ <=> 12-epi-fischerindole_G + succinate + CO2 + H2O 1.14.20.14 hapalindole-type alkaloid chlorinase

M
an_L-threonyl-[L-threonyl-carrier_protein] + 2-oxoglutarate + O2 + Cl- + H+ <=> a_4-chloro-L-threonyl-[L-threonyl-carrier_protein] + succinate + CO2 + H2O 1.14.20.15 L-threonyl-[L-threonyl-carrier protein] 4-chlorinase

scopoletin + 2-oxoglutarate + O2 <=> fraxetin + succinate + CO2 1.14.11.60 scopoletin 8-hydroxylase

succinyl-CoA + mesaconate <=> 2-methylfumaryl-CoA + succinate 2.8.3.26 succinyl-CoA:mesaconate CoA transferase

BMK
feruloyl-CoA + 2-oxoglutarate + O2 <=> trans-6-hydroxyferuloyl-CoA + succinate + CO2 1.14.11.61 feruloyl-CoA 6-hydroxylase

MK
a_[protein]-L-tyrosine + 2-oxoglutarate + O2 <=> a_[protein]-(3S)-3-hydroxy-L-lysine + succinate + CO2 1.14.11.63 peptidyl-lysine (3S)-dioxygenase

[histone_H3]_N6-methyl-L-lysine-36 + 2-oxoglutarate + O2 <=> histone_H3(K36) + formaldehyde + succinate + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase


[histone_H3]_N6,N6,N6-trimethyl-L-lysine-9 + 2-oxoglutarate + O2 <=> [histone_H3]_N6,N6-dimethyl-L-lysine-9 + formaldehyde + succinate + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase



[histone_H3]_N6,N6-dimethyl-L-lysine-9 + 2-oxoglutarate + O2 <=> [histone_H3]_N6-methyl-L-lysine-9 + formaldehyde + succinate + CO2 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase



[histone_H3]-N6,N6-dimethyl-L-lysine-4 + 2-oxoglutarate + O2 <=> [histone_H3]-N6-methyl-L-lysine-4 + formaldehyde + succinate + CO2 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase
1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase



[histone_H3]-N6-methyl-L-lysine-4 + 2-oxoglutarate + O2 <=> histone_H3(K4) + formaldehyde + succinate + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase
1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase





Glutarate + 2-oxoglutarate + O2 <=> (S)-2-hydroxyglutarate + succinate + CO2 1.14.11.64 glutarate dioxygenase

MK
[histone_H3]_N6,N6-dimethyl-L-lysine-9 + 2-oxoglutarate + O2 <=> [histone_H3]-L-lysine-9 + formaldehyde + succinate + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase




[histone_H3]_N6-methyl-L-lysine-9 + 2-oxoglutarate + O2 <=> [histone_H3]-L-lysine-9 + formaldehyde + succinate + CO2 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase



histone_H3_N6,N6,N6-trimethyl-L-lysine27 + 2-oxoglutarate + O2 <=> [histone_H3]_N6-methyl-L-lysine-27 + formaldehyde + succinate + CO2 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase

histone_H3_N6,N6,N6-trimethyl-L-lysine27 + 2-oxoglutarate + O2 <=> [histone_H3]-N6,N6-dimethyl-L-lysine_27 + formaldehyde + succinate + CO2 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase
1.14.18.B1


[histone_H3]-N6,N6-dimethyl-L-lysine_27 + 2-oxoglutarate + O2 <=> [histone_H3]_N6-methyl-L-lysine-27 + formaldehyde + succinate + CO2 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase


[histone_H3]_N6,N6,N6-trimethyl-L-lysine-36 + 2-oxoglutarate + O2 <=> [histone_H3]_N6-methyl-L-lysine-36 + formaldehyde + succinate + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase


[histone_H3]_N6,N6,N6-trimethyl-L-lysine-36 + 2-oxoglutarate + O2 <=> histone_H3_N6,N6-dimethyl-L-lysine36 + formaldehyde + succinate + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase



4-coumaroyl-CoA + 2-oxoglutarate + O2 <=> 2,4-dihydroxycinnamoyl-CoA + succinate + CO2 1.14.11.62 trans-4-coumaroyl-CoA 2-hydroxylase

MK
7-deoxycylindrospermopsin + O2 + 2-oxoglutarate <=> cylindrospermopsin + succinate + CO2 1.14.11.70 7-deoxycylindrospermopsin hydroxylase

M
7-deoxycylindrospermopsin + O2 + 2-oxoglutarate <=> 7-epi-cylindrospermopsin + succinate + CO2 1.14.11.70 7-deoxycylindrospermopsin hydroxylase

M
methylphosphonate + O2 + 2-oxoglutarate <=> hydroxymethylphosphonate + succinate + CO2 1.14.11.71 methylphosphonate hydroxylase

MK
L-isoleucine + 2-oxoglutarate + O2 <=> (3S)-3'-hydroxy-L-isoleucine + succinate + CO2 1.14.11.74 L-isoleucine 31-dioxygenase

(3S)-3'-hydroxy-L-isoleucine + 2-oxoglutarate + O2 <=> (4S)-31,4-dihydroxy-L-isoleucine + succinate + CO2 1.14.11.75 31-hydroxy-L-isoleucine 4-dioxygenase

filaggrin_L-Arg + O2 + 2-oxoglutarate <=> [protein]-(3R)-3-hydroxy-L-arginine + succinate + CO2 1.14.11.73 [protein]-arginine 3-hydroxylase

succinate + GTP + CoA <=> succinyl-CoA + GDP + phosphate 6.2.1.4 succinate---CoA ligase (GDP-forming)

BMK
succinate + CoA + ATP <=> succinyl-CoA + ADP + phosphate 6.2.1.13 acetate---CoA ligase (ADP-forming)
6.2.1.4 succinate---CoA ligase (GDP-forming)
6.2.1.5 succinate---CoA ligase (ADP-forming)



BMK
ubiquinone + succinate <=> ubiquinol + fumarate 1.3.5.1 succinate dehydrogenase
1.3.5.4 fumarate reductase (quinol)


M
N6,N6,N6-Trimethyl-L-lysine + 2-oxoglutarate + O2 <=> 3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2 1.14.11.8 trimethyllysine dioxygenase

M
naringenin + 2-oxoglutarate + O2 <=> (+)-dihydrokaempferol + succinate + CO2 1.14.11.9 flavanone 3-dioxygenase

MK
eriodictyol + 2-oxoglutarate + O2 <=> taxifolin + succinate + CO2 1.14.11.9 flavanone 3-dioxygenase

MK
gibberellin_a9 + 2-oxoglutarate + O2 <=> gibberellin_a4 + succinate + CO2 1.14.11
1.14.11.15 gibberellin 3beta-dioxygenase


MK
gibberellin_a15 + 2-oxoglutarate + O2 <=> gibberellin_a37 + succinate + CO2 1.14.11
1.14.11.15 gibberellin 3beta-dioxygenase


M
gibberellin_a5 + O2 + 2-oxoglutarate <=> gibberellin + succinate + CO2 1.14.11
1.14.11.15 gibberellin 3beta-dioxygenase


M
O-succinyl-L-homoserine + H2O <=> 2-oxobutyrate + succinate + NH3 + H+ 2.5.1.48 cystathionine gamma-synthase
4.3.1
4.4.1.13 cysteine-S-conjugate beta-lyase



K
O-succinyl-L-homoserine + Sulfide <=> H+ + L-homocysteine + succinate 2.5.1
2.5.1.48 cystathionine gamma-synthase
2.5.1.49 O-acetylhomoserine aminocarboxypropyltransferase



K
O-succinyl-L-homoserine + methanethiol <=> L-methionine + succinate + H+ 2.5.1.48 cystathionine gamma-synthase

succinyl-CoA + Glutarate <=> succinate + glutaryl-CoA 2.8.3.13 succinate---hydroxymethylglutarate CoA-transferase
2.8.3.18 succinyl-CoA:acetate CoA-transferase


M
succinyl-CoA + acetoacetate <=> succinate + acetoacetyl-CoA 2.8.3.18 succinyl-CoA:acetate CoA-transferase
2.8.3.5 3-oxoacid CoA-transferase


BMK
succinyl-CoA + 4-methyl-3-oxoadipate <=> succinate + 4-methyl-3-oxoadipyl-CoA 2.8.3.6 3-oxoadipate CoA-transferase

M
menaquinol + fumarate <=> menaquinone + succinate 1.3.5.1 succinate dehydrogenase
1.3.5.4 fumarate reductase (quinol)


M
(+)-dihydrokaempferol + 2-oxoglutarate + O2 <=> kaempferol + succinate + CO2 + H2O + H+ 1.14.20.5 flavone synthase I
1.14.20.6 flavonol synthase


MK
(2R)-naringenin + 2-oxoglutarate + O2 <=> (-)-dihydrokaempferol + succinate + CO2 1.14.20.6 flavonol synthase

taxifolin + 2-oxoglutarate + O2 <=> quercetin + succinate + CO2 + H2O 1.14.20.4 anthocyanidin synthase
1.14.20.6 flavonol synthase


MK
naringenin + 2-oxoglutarate + O2 <=> apigenin + succinate + CO2 + H2O + H+ 1.14.20.4 anthocyanidin synthase
1.14.20.5 flavone synthase I


MK
protein_L-lysine + O2 + 2-oxoglutarate <=> [procollagen]-(2S,5R)-5-hydroxy-L-lysine + CO2 + succinate 1.14.11.4 procollagen-lysine 5-dioxygenase

M
gibberellin_a5 + O2 + 2-oxoglutarate <=> gibberellin_A6 + succinate + CO2 1.14.11
1.14.11.15 gibberellin 3beta-dioxygenase


M
eriodictyol + 2-oxoglutarate + O2 <=> luteolin + succinate + CO2 + H2O 1.14.20.5 flavone synthase I

MK
pinocembrin + O2 + 2-oxoglutarate <=> chrysin + succinate + H2O + CO2 1.14.20.5 flavone synthase I

MK
dihydromyricetin + 2-oxoglutarate + O2 <=> myricetin + succinate + CO2 + H2O 1.14.20.6 flavonol synthase

MK
caldariellaquinone + succinate <=> caldariellaquinol + fumarate 1.3.5.1 succinate dehydrogenase

oripavine + 2-oxoglutarate + O2 <=> morphinone + formaldehyde + succinate + CO2 1.14.11.31 thebaine 6-O-demethylase

MK
[histone_H3]_N6,N6,N6-trimethyl-L-lysine-4 + 2-oxoglutarate + O2 <=> [histone_H3]-N6,N6-dimethyl-L-lysine-4 + formaldehyde + succinate + CO2 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase

thebaine + 2-oxoglutarate + O2 <=> oripavine + formaldehyde + succinate + CO2 1.14.11.32 codeine 3-O-demethylase

MK
L-aspartate + fumarate <=> H+ + iminosuccinate + succinate 1.4.3.16 L-aspartate oxidase
1.5.99


N1-methyl-2'-deoxyadenosine_5'-triphosphate + 2-oxoglutarate + O2 <=> dATP + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

1-methyl-dAMP + 2-oxoglutarate + O2 <=> dAMP + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

1-methyladenine + O2 + 2-oxoglutarate <=> adenine + CO2 + formaldehyde + succinate 1.14.11.33 DNA oxidative demethylase

rhodoquinol-3 + fumarate <=> rhodoquinone + succinate 1.3.5.4 fumarate reductase (quinol)

M
formyl-CoA + succinate <=> formate + succinyl-CoA 2.8.3.16 formyl-CoA transferase
2.8.3.18 succinyl-CoA:acetate CoA-transferase


propionyl-CoA + succinate <=> propionate + succinyl-CoA 2.8.3
2.8.3.1 propionate CoA-transferase
2.8.3.18 succinyl-CoA:acetate CoA-transferase
2.8.3.M4




BMK
L-leucine + 2-oxoglutarate + O2 <=> 4-hydroxy-L-leucine + succinate + CO2 1.14.11
1.14.11.45 L-isoleucine 4-hydroxylase


L-methionine + 2-oxoglutarate + O2 <=> methionine_sulfoxide + succinate + CO2 1.14.11
1.14.11.45 L-isoleucine 4-hydroxylase
1.14.11.74 L-isoleucine 31-dioxygenase



N1-methyladenine_in_DNA + 2-oxoglutarate + O2 <=> adenine_in_DNA + CO2 + formaldehyde + succinate 1.14.11.33 DNA oxidative demethylase

N3-methylcytosine_in_DNA + 2-oxoglutarate + O2 <=> cytosine_(in_DNA) + CO2 + formaldehyde + succinate + H+ 1.14.11.33 DNA oxidative demethylase

2-oxoglutarate + O2 + L-arginine + H+ <=> ethylene + CO2 + succinate + guanidine + L-pyrroline-5-carboxylate + H2O 1.13.12.19 2-oxoglutarate dioxygenase (ethene-forming)
1.14.11
1.14.20.7 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)



12-epi-hapalindole_C + 2-oxoglutarate + O2 + Cl- + H+ <=> 12-epi-hapalindole_E + succinate + CO2 + H2O 1.14.20.14 hapalindole-type alkaloid chlorinase

ambiguine_C + 2-oxoglutarate + O2 + Cl- + H+ <=> ambiguine_B + succinate + CO2 + H2O 1.14.20.14 hapalindole-type alkaloid chlorinase

ambiguine_H + 2-oxoglutarate + O2 + Cl- + H+ <=> ambiguine_A + succinate + CO2 + H2O 1.14.20.14 hapalindole-type alkaloid chlorinase

ambiguine_I + 2-oxoglutarate + O2 + Cl- + H+ <=> ambiguine_E + succinate + CO2 + H2O 1.14.20.14 hapalindole-type alkaloid chlorinase

ambiguine_L + 2-oxoglutarate + O2 + Cl- + H+ <=> ambiguine_K + succinate + CO2 + H2O 1.14.20.14 hapalindole-type alkaloid chlorinase

caffeoyl-CoA + 2-oxoglutarate + O2 <=> 6'-hydroxycaffeoyl-CoA + succinate + CO2 1.14.11
1.14.11.61 feruloyl-CoA 6-hydroxylase


M
[histone_H4]-N6-methyl-L-lysine_20 + 2-oxoglutarate + O2 <=> [histone_H4]-L-lysine_20 + formaldehyde + succinate + CO2 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase


gibberellin_44 + 2-oxoglutarate + O2 <=> Gibberellin_19 + succinate + CO2 1.14.11.12 gibberellin-44 dioxygenase

Procollagen_L-proline + 2-oxoglutarate + O2 <=> procollagen_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.12 gibberellin-44 dioxygenase
1.14.11.2 procollagen-proline 4-dioxygenase


Peptide_L-aspartate + 2-oxoglutarate + O2 <=> peptide_3-hydroxy-L-aspartate + succinate + CO2 1.14.11.16 peptide-aspartate beta-dioxygenase

a_dihydroflavonol + 2-oxoglutarate + O2 <=> a_flavonol + succinate + CO2 + H2O 1.14.20.6 flavonol synthase

N2-succinylglutamate + H2O <=> L-glutamate + succinate 3.5.1.96 succinylglutamate desuccinylase

BMK
succinate + a_quinone <=> fumarate + a_quinol 1.3.5.1 succinate dehydrogenase
1.3.5.4 fumarate reductase (quinol)


BK
L-arginine + 2-oxoglutarate + O2 <=> Nomega-hydroxy-L-arginine + succinate + CO2 1.14.11
1.14.20.7 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)


M
fumitremorgin_B + 2-oxoglutarate + 2 O2 + reduced_acceptor <=> verruculogen + succinate + CO2 + H2O + acceptor 1.14.11.38 verruculogen synthase

BK
2-aminoethylphosphonate + 2-oxoglutarate + O2 <=> 2-amino-1-hydroxyethylphosphonate + succinate + CO2 1.14.11.46 2-aminoethylphosphonate dioxygenase

K
[2-(trimethylamino)ethyl]phosphonate + 2-oxoglutarate + O2 <=> [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + succinate + CO2 1.14.11.72 [2-(trimethylamino)ethyl]phosphonate dioxygenase

N6,N6,N6-Trimethyl-L-lysine + 2-oxoglutarate + O2 <=> (3S)-3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2 1.14.11.8 trimethyllysine dioxygenase

BK
5-Hydroxymethyluracil + 2-oxoglutarate + O2 <=> 5-Formyluracil + succinate + CO2 1.14.11.6 thymine dioxygenase

5-Formyluracil + 2-oxoglutarate + O2 <=> Uracil-5-carboxylate + succinate + CO2 1.14.11.6 thymine dioxygenase

succinate + acceptor <=> fumarate + reduced_acceptor 1.3.5.1 succinate dehydrogenase
1.3.5.4 fumarate reductase (quinol)
1.3.99



protein_N6,N6-dimethyl-L-lysine + 2-oxoglutarate + O2 <=> protein_N6-methyl-L-lysine + succinate + formaldehyde + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase
1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase
1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase






Leucocyanidin + 2-oxoglutarate + O2 + H+ <=> cyanidin + succinate + CO2 + 2 H2O 1.14.20.4 anthocyanidin synthase

K
liquiritigenin + 2-oxoglutarate + O2 <=> 7,4''-dihydroxyflavone + succinate + CO2 + H2O 1.14.20.5 flavone synthase I

K
succinate + FAD <=> fumarate + FADH2 1.3.1.6 fumarate reductase (NADH)
1.3.5.1 succinate dehydrogenase


B
(2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O <=> 2-hydroxy-2,4-pentadienoate + succinate 3.7.1.14 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase

K
gibberellin_a20 + 2-oxoglutarate + O2 <=> Gibberellin_A29 + succinate + CO2 1.14.11
1.14.11.13 gibberellin 2beta-dioxygenase


MK
succinate + ITP + CoA <=> succinyl-CoA + IDP + phosphate 6.2.1.4 succinate---CoA ligase (GDP-forming)

K
gibberellin_a9 + 2-oxoglutarate + O2 <=> gibberellin_A51 + succinate + CO2 1.14.11
1.14.11.13 gibberellin 2beta-dioxygenase


MK
Gibberellin_A24 + 2-oxoglutarate + O2 <=> Gibberellin_A36 + succinate + CO2 1.14.11

MK
gibberellin_a4 + 2-oxoglutarate + O2 <=> gibberellin_A34 + succinate + CO2 1.14.11
1.14.11.13 gibberellin 2beta-dioxygenase


MK
pinocembrin + 2-oxoglutarate + O2 <=> 3,5,7-trihydroxyflavanone + succinate + CO2 1.14.11.9 flavanone 3-dioxygenase

MK
3,4-cis-leucodelphinidin + O2 + 2-oxoglutarate <=> delphinidin + succinate + CO2 + H2O + H+ 1.14.20
1.14.20.4 anthocyanidin synthase


MK
(2S)-dihydrotricetin + 2-oxoglutarate + O2 <=> dihydromyricetin + succinate + CO2 1.14.11.9 flavanone 3-dioxygenase

MK
succinyl-CoA + Itaconate <=> succinate + itaconyl-CoA 2.8.3
2.8.3.20 succinyl-CoA---D-citramalate CoA-transferase
2.8.3.22 succinyl-CoA---L-malate CoA-transferase



MK
2,4-Dichlorophenoxyacetic_acid + 2-oxoglutarate + O2 <=> 2,4-Dichlorophenol + glyoxylate + succinate + CO2 1.14.11

MK
gibberellin_A12 + O2 + 2-oxoglutarate <=> gibberellin_a15 + CO2 + succinate 1.14.11
1.14.11.12 gibberellin-44 dioxygenase


MK
gibberellin_a15 + 2-oxoglutarate + O2 <=> Gibberellin_A24 + succinate + CO2 + H2O 1.14.11.12 gibberellin-44 dioxygenase
1.14.20


MK
Gibberellin_A53 + O2 + 2-oxoglutarate <=> gibberellin_44 + CO2 + succinate 1.14.11
1.14.11.12 gibberellin-44 dioxygenase


MK
gibberellin_44 + 2-oxoglutarate + O2 <=> Gibberellin_19 + succinate + CO2 + H2O 1.14.11.12 gibberellin-44 dioxygenase

MK
Gibberellin_19 + O2 + 2-oxoglutarate <=> H+ + gibberellin_a20 + CO2 + succinate 1.14.11
1.14.11.12 gibberellin-44 dioxygenase


MK
pentanesulfonic_acid + 2-oxoglutarate + O2 <=> sulfite + pentanal + succinate + CO2 1.14.11.17 taurine dioxygenase

succinate + hydroxylamine <=> succinyl_hydroxamate + H2O 3.5.1.3 omega-amidase

6,7-Dehydrohyoscyamine + 2-oxoglutarate + O2 <=> Scopolamine + succinate + CO2 1.14.11.11 hyoscyamine (6S)-dioxygenase
1.14.20.13 6beta-hydroxyhyoscyamine epoxidase


penicillin_G + 2-oxoglutarate + O2 <=> phenylacetyl-7-aminodeacetoxycephalosporanic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

ampicillin + 2-oxoglutarate + O2 <=> cephalexin + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

O-succinyl-L-homoserine <=> succinate + pyruvate + NH3 2.5.1.48 cystathionine gamma-synthase

fumarate + FMNH2 <=> succinate + FMN 1.3.1.6 fumarate reductase (NADH)

protein + 2-oxoglutarate + O2 <=> (2S,5R)-_5-hydroxy-L-lysine-[procollagen] + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

K
cis-3,4-leucopelargonidin + 2-oxoglutarate + O2 <=> pelargonidin + succinate + CO2 + 2 H2O 1.14.20.4 anthocyanidin synthase

K
O-succinyl-L-homoserine + L-selenocysteine <=> L-selenocystathionine + succinate 2.5.1.48 cystathionine gamma-synthase

K
deacetylcephalosporin_C + H2O + 2 succinate + 2 CO2 <=> Penicillin_N + 2 2-oxoglutarate + 2 O2 not assigned

7beta-(5-D-Aminoadipamido)-3-carbamoyloxymethylceph-3-em-4-carboxylic_acid + 2-oxoglutarate + O2 <=> 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin_C + succinate + CO2 not assigned

K
4-Chlorophenoxyacetate + 2-oxoglutarate + O2 <=> 4-Chlorophenol + glyoxylate + succinate + CO2 1.14.11

K
Leucocyanidin + 2-oxoglutarate + O2 <=> taxifolin + succinate + CO2 + H2O 1.14.20.4 anthocyanidin synthase

K
cis-3,4-leucopelargonidin + 2-oxoglutarate + O2 <=> dihydrokaempferol + succinate + CO2 + H2O 1.14.20.4 anthocyanidin synthase

K
pentahydroxyflavanone + 2-oxoglutarate + O2 <=> tricetin + succinate + CO2 + H2O 1.14.20.5 flavone synthase I

K
2-chloro-3-oxohexanedioic_acid <=> Chloroacetate + succinate not assigned

K
2-Naphtylmethylsuccinic_acid + succinyl-CoA <=> Naphthyl-2-methyl-succinyl-CoA + succinate 2.8.3

K
Leucocyanidin + 2-oxoglutarate + O2 <=> cis-dihydroquercetin + succinate + CO2 + H2O 1.14.20.4 anthocyanidin synthase

liquiritigenin + 2-oxoglutarate + O2 <=> 3,7,4'-trihydroxyflavanone + succinate + CO2 1.14.11.9 flavanone 3-dioxygenase

K
butin + 2-oxoglutarate + O2 <=> fustin + succinate + CO2 1.14.11.9 flavanone 3-dioxygenase

K
3,5,7-trihydroxyflavanone + 2-oxoglutarate + O2 <=> galangin + succinate + CO2 + H2O 1.14.20.6 flavonol synthase

K
protein_N6-methyl-L-lysine + 2-oxoglutarate + O2 <=> protein + succinate + formaldehyde + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase



protein_N6,N6-dimethyl-L-lysine + 2 2-oxoglutarate + 2 O2 <=> protein + 2 succinate + 2 formaldehyde + 2 CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase


7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine_in_tRNA(Phe) + 2-oxoglutarate + O2 <=> 7-(2-Hydroxy-3-amino-3-carboxypropyl)wyosine_in_tRNA(Phe) + succinate + CO2 1.14.11.42 tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase

OA-6129_A + 2-oxoglutarate + O2 <=> OA-6129_B2 + succinate + CO2 1.14.20

K
2,3-Dihydrothienamycin + 2-oxoglutarate + O2 <=> Thienamycin + succinate + CO2 + H2O 1.14.20

K
Epithienamycin_F + 2-oxoglutarate + O2 <=> Epithienamycin_E + succinate + CO2 + H2O 1.14.20

K
Epithienamycin_E + 2-oxoglutarate + O2 <=> MM_4550 + succinate + CO2 1.14.20

K
DNA_containing_5-methylcytosine + 2-oxoglutarate + O2 <=> DNA_5-hydroxymethylcytosine + succinate + CO2 1.14.11

Kdo2-lipid_A + 2-oxoglutarate + O2 <=> (S)-2-Hydroxymyristate-modified_lipid_A + succinate + CO2 1.14.11

K
L-lysine + 2-oxoglutarate + O2 + Cl- + H+ <=> 4-Chloro-L-lysine + succinate + CO2 + H2O 1.14.20

K
gamma-L-Glutamyl-L-propargylglycine + 2-oxoglutarate + O2 <=> L-gamma-Glutamyl-(3R)-L-beta-ethynylserine + succinate + CO2 1.14.11

K
Protein_N6,N6,N6-trimethyl-L-lysine + 2 2-oxoglutarate + 2 O2 <=> protein_N6-methyl-L-lysine + 2 succinate + 2 formaldehyde + 2 CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase
1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase



Protein_N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 <=> protein_N6,N6-dimethyl-L-lysine + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase
1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase
1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase




Protein_N6,N6,N6-trimethyl-L-lysine + 3 2-oxoglutarate + 3 O2 <=> protein + 3 succinate + 3 formaldehyde + 3 CO2 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase

indole-3-acetic_acid + 2-oxoglutarate + O2 <=> 2-oxoindole-3-acetate + succinate + CO2 1.14.11

K
Procollagen_L-proline + 2-oxoglutarate + O2 <=> [procollagen]_trans_4-hyroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

M
cis-3,4-leucopelargonidin + 2-oxoglutarate + O2 <=> a_(4S)-_2,3-dehydroflavan-3,4-diol + succinate + CO2 + H2O + H+ 1.14.20.4 anthocyanidin synthase

M
[protein]-L-aspartate + O2 + 2-oxoglutarate <=> peptide_3-hydroxy-L-aspartate + succinate + CO2 1.14.11.16 peptide-aspartate beta-dioxygenase

[hypoxia_inducible_factor_(HIF)_alpha_subunit]-L-proline + 2-oxoglutarate + O2 <=> [hypoxia_inducible_factor_(HIF)_alpha_subunit]-trans_4-hyroxy-L-proline + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

[hypoxia_inducible_factor_(HIF)_alpha_subunit]-L-asparagine + 2-oxoglutarate + O2 <=> [hypoxia_inducible_factor_(HIF)_alpha_subunit]-(3S)-hydroxy-L-asparagine + succinate + CO2 1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase

Gibberellin_A29 + 2-oxoglutarate + O2 <=> H+ + Gibberellin_A29-catabolite + succinate + CO2 + H2O 1.14.20

M
2beta-hydroxygibberellin_1 + 2-oxoglutarate + O2 <=> H+ + Gibberellin_A8-catabolite + succinate + CO2 + H2O 1.14.20

M
2-hydroxyethylphosphonate + 2-oxoglutarate + O2 <=> 1,2-dihydroxyethylphosphonate + succinate + CO2 1.14.11

M
DNA-base-CH3 + O2 + 2-oxoglutarate <=> nucleobase_within_DNA + CO2 + formaldehyde + succinate 1.14.11.33 DNA oxidative demethylase

neopentalenolactone_D + O2 + 2-oxoglutarate <=> neopentalenolactone_E + succinate + CO2 + H2O 1.14.20

M
neopentalenolactone_E + O2 + 2-oxoglutarate <=> neopentalenolactone_F + succinate + CO2 1.14.11

M
L-threonine + 2-oxoglutarate + O2 <=> L-4-hydroxythreonine + succinate + CO2 1.14.11

3,7-O-dimethylquercetin + 2-oxoglutarate + O2 <=> 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + succinate + CO2 1.14.11

M
3,7,4''-trimethylquercetin + 2-oxoglutarate + O2 <=> 3,7,4''-trimethylquercetagetin + succinate + CO2 1.14.11

M
ferulic_acid + 2-oxoglutarate + O2 <=> (E)-6''-hydroxyferulate + succinate + CO2 not assigned

M
fumitremorgin_B + 2-oxoglutarate + O2 + ascorbate <=> verruculogen + succinate + CO2 + H2O + dehydroascorbate 1.14.11.38 verruculogen synthase

M
luteoforol + O2 + 2-oxoglutarate + H+ <=> luteolinidin + succinate + CO2 + H2O 1.14.20

M
Apiforol + 2-oxoglutarate + O2 <=> apigeninidin + succinate + CO2 + H2O 1.14.20

M
7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37_in_tRNAPhe + 2-oxoglutarate + O2 <=> 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37_in_tRNAPhe + succinate + CO2 1.14.11.42 tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase

gardenin_B + 2-oxoglutarate + O2 <=> nevadensin + formaldehyde + succinate + CO2 1.14.11

M
8-hydroxy-salvigenin + 2-oxoglutarate + O2 <=> pilosin + formaldehyde + succinate + CO2 1.14.11

M
succinyl-CoA + citramalate <=> citramalyl-CoA + succinate 2.8.3.22 succinyl-CoA---L-malate CoA-transferase

electron-transfer_quinone + succinate <=> electron-transfer_quinol + fumarate 1.3.5.4 fumarate reductase (quinol)

electron-transfer_quinone + succinate <=> electron-transfer_quinol + fumarate 1.3.5.1 succinate dehydrogenase

M
FR-900098 + 2-oxoglutarate + O2 <=> FR-33289 + succinate + CO2 1.14.11

M
O-succinyl-L-homoserine <=> succinate + 2-aminobut-2-enoate + H+ not assigned

2-aminoethylphosphonate + O2 + 2-oxoglutarate <=> (1R)-[2-amino-1-hydroxyethyl]phosphonic_acid + succinate + CO2 1.14.11.46 2-aminoethylphosphonate dioxygenase

M
4-oxo-4-sulfanylbutanoate + H2O <=> succinate + Sulfide + H+ 3.13.1

M
fusicocca-2,10(14)-diene-8beta,16-diol + 2-oxoglutarate + O2 <=> fusicocca-1,10(14)-diene-3,8beta,16-triol + succinate + CO2 1.14.11

M
fusicocca-2,10(14)-diene-8beta,16-diol + 2-oxoglutarate + O2 <=> 8beta-hydroxyfusicocca-1,10(14)-diene-16-al + succinate + CO2 + H2O 1.14.20

M
sulfinosuccinate + H2O <=> succinate + sulfite + H+ not assigned

M
preandiloid_C + 2-oxoglutarate + ascorbate + O2 <=> andiconin + succinate + CO2 + dehydroascorbate + H2O 1.14.20

M
andilesin_C + 2-oxoglutarate + O2 <=> anditomin + succinate + CO2 + H2O 1.14.20

M
L-leucine + 2-oxoglutarate + O2 <=> 5-hydroxy-leucine + succinate + CO2 1.14.11

M
5-hydroxy-leucine + 2-oxoglutarate + O2 <=> 5,5-dihydroxy-leucine + succinate + CO2 1.14.11

M
L-hTyr + 2-oxoglutarate + O2 <=> 3-hydroxy-L-homotyrosine + succinate + CO2 1.14.11

M
(2R,6Z)-2-hydroxy-6-(hydroxymethylidene)-2,5-dimethylcyclohex-4-ene-1,3-dione + O2 + 2-oxoglutarate <=> stipitaldehyde + succinate + CO2 + H2O 1.14.20

M
6-dehydroguadinomine_B + 2-oxoglutarate + O2 <=> guadinomine_B + succinate + CO2 1.14.11.M1

M
cyclopeptine + 2-oxoglutarate + O2 <=> dehydrocyclopeptine + succinate + CO2 + H2O 1.14.20

M
dehydrocyclopeptine + 2-oxoglutarate + O2 <=> (-)-cyclopenine + succinate + CO2 1.14.11

M
4''-methoxycyclopeptine + 2-oxoglutarate + O2 <=> 4''-methoxydehydrocyclopeptine + succinate + CO2 + H2O 1.14.20

M
4''-methoxydehydrocyclopeptine + 2-oxoglutarate + O2 <=> (-)-4''-methoxycyclopenine + succinate + CO2 1.14.11

M
N-3-fumaramoyl-(S)-2,3-diaminopropanoyl-[DdaD_non-ribosomal_peptide_synthase] + 2-oxoglutarate + O2 <=> N-3-(R,R)-epoxysuccinamoyl-(S)-2,3-diaminopropanoyl-[DdaD_non-ribosomal_peptide_synthase] + succinate + CO2 1.14.11.M2

M
gibberellin_A51 + 2-oxoglutarate + O2 <=> H+ + Gibberellin_A51-catabolite + succinate + CO2 + H2O 1.14.20

M
H+ + glycolate <=> acetate + succinate + CO2 + H2O not assigned

M
primary_alkyl_sulfate_ester + O2 + 2-oxoglutarate <=> an_aldehyde + succinate + CO2 + sulfate + H+ 1.14.11.ak

(2R,3R)-dihydroflavonol + 2-oxoglutarate + O2 <=> 3-hydroxyflavone + succinate + CO2 + H2O 1.14.20.6 flavonol synthase

vindolidine + 2-oxoglutarate + O2 <=> deacetylvindorosine + succinate + CO2 1.14.11.20 deacetoxyvindoline 4-hydroxylase

M
ambiguine_J + 2-oxoglutarate + O2 + Cl- + H+ <=> ambiguine_D + succinate + CO2 + H2O 1.14.20.14 hapalindole-type alkaloid chlorinase

butyl_sulfate + O2 + 2-oxoglutarate <=> Butyraldehyde + succinate + CO2 + sulfate + H+ 1.14.11.ak

2-ethylhexyl_sulfate + O2 + 2-oxoglutarate <=> 2-ethylhexanal + succinate + CO2 + sulfate + H+ 1.14.11.ak

1-pentyl_sulfate + O2 + 2-oxoglutarate <=> pentanal + succinate + CO2 + sulfate + H+ 1.14.11.ak

1-hexyl_sulfate + O2 + 2-oxoglutarate <=> hexanal + succinate + CO2 + sulfate + H+ 1.14.11.ak

1-heptyl_sulfate + O2 + 2-oxoglutarate <=> Heptanal + succinate + CO2 + sulfate + H+ 1.14.11.ak

1-octyl_sulfate + O2 + 2-oxoglutarate <=> octanal + succinate + CO2 + sulfate + H+ 1.14.11.ak

1-nonyl_sulfate + O2 + 2-oxoglutarate <=> Nonanal + succinate + CO2 + sulfate + H+ 1.14.11.ak

1-decyl_sulfate + O2 + 2-oxoglutarate <=> decanal + succinate + CO2 + sulfate + H+ 1.14.11.ak

Dodecyl_sulfate + O2 + 2-oxoglutarate <=> dodecanal + succinate + CO2 + sulfate + H+ 1.14.11.ak

[protein]-Nomega,N''omega-dimethyl-L-arginine + O2 + 2-oxoglutarate <=> [protein]-Nomega-methyl-L-arginine + succinate + CO2 + formaldehyde not assigned

[protein]-Nomega-methyl-L-arginine + O2 + 2-oxoglutarate <=> filaggrin_L-Arg + succinate + CO2 + formaldehyde not assigned

[protein]-Nomega,Nomega-dimethyl-L-arginine + O2 + 2-oxoglutarate <=> [protein]-Nomega-methyl-L-arginine + succinate + CO2 + formaldehyde not assigned

[protein]-Nomega,N''omega-dimethyl-L-arginine + O2 + 2-oxoglutarate <=> filaggrin_L-Arg + succinate + CO2 + formaldehyde 1.14.11.M17

[protein]-Nomega,Nomega-dimethyl-L-arginine + O2 + 2-oxoglutarate <=> filaggrin_L-Arg + succinate + CO2 + formaldehyde 1.14.11.M18

[histone_H3]_N6,N6,N6-trimethyl-L-lysine-79 + 2-oxoglutarate + O2 <=> [histone_H3]_N6,N6-dimethyl-L-lysine-79 + formaldehyde + succinate + CO2 not assigned

[histone_H4]-N6,N6,N6-trimethyl-L-lysine20 + 2-oxoglutarate + O2 <=> [histone_H4]-N6,N6-dimethyl-L-lysine20 + formaldehyde + succinate + CO2 not assigned

[histone_H3]_N6,N6-dimethyl-L-lysine-79 + 2-oxoglutarate + O2 <=> [histone_H3]_N6-methyl-L-lysine-79 + formaldehyde + succinate + CO2 not assigned

[histone_H4]-N6,N6-dimethyl-L-lysine20 + 2-oxoglutarate + O2 <=> [histone_H4]-N6-methyl-L-lysine_20 + formaldehyde + succinate + CO2 not assigned

[histone_H3]_N6-methyl-L-lysine-27 + 2-oxoglutarate + O2 <=> histone_H3(K27) + formaldehyde + succinate + CO2 not assigned

[histone_H3]_N6-methyl-L-lysine-79 + 2-oxoglutarate + O2 <=> [histone_H3]-L-lysine-79 + formaldehyde + succinate + CO2 1.14.11

DIMBOA-glucoside + 2-oxoglutarate + O2 <=> TRIMBOA-beta-D-glucoside + succinate + CO2 1.14.11.M27

M
alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid_A_form_C_(P._putida) + 2-oxoglutarate + O2 <=> alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid_A_form_A_(P._putida) + succinate + CO2 1.14.11

M
prekainate + 2-oxoglutarate + O2 <=> kainate + succinate + CO2 + H2O 1.14.11

M
prekainate + 2-oxoglutarate + O2 + H+ <=> kainate_lactone + succinate + H2O + CO2 1.14.11

M
N-(7''-carboxy-7''-demethylgeranyl)-L-glutamate + O2 + 2-oxoglutarate <=> isodomoate_A + succinate + CO2 + H2O 1.14.11

M
N-geranyl-L-glutamate + O2 + 2-oxoglutarate <=> dainate_A + succinate + CO2 + H2O + H+ 1.14.11

(1S)-1-[(2S)-2-amino-4-methylpentanamido]ethyl(methoxy)phosphinate + 2-oxoglutarate + O2 <=> 1-[(2S)-2-amino-4-methylpentanamido]ethenyl(methoxy)phosphinate + succinate + CO2 + H2O 1.14.19

M
N1-methyladenine_in_RNA + 2-oxoglutarate + O2 <=> adenine_in_RNA + CO2 + formaldehyde + succinate 1.14.11.54 mRNA N1-methyladenine demethylase

N3-methylcytosine_in_RNA + 2-oxoglutarate + O2 <=> RNA-cytosine + CO2 + formaldehyde + succinate + H+ 1.14.11.54 mRNA N1-methyladenine demethylase

2-methylthiocytosine32_in_tRNA + 2-oxoglutarate + O2 <=> 2-thiocytosine32_in_tRNA + formaldehyde + succinate + CO2 1.14.11

[2-(trimethylamino)ethyl]phosphonate + O2 + 2-oxoglutarate <=> (1R)-(1-hydroxy-2-trimethylamino)ethylphosphonate + succinate + CO2 1.14.11.72 [2-(trimethylamino)ethyl]phosphonate dioxygenase

M
menaquinol-9 + fumarate <=> menaquinone-9(2H) + succinate 1.3.5.1 succinate dehydrogenase

menaquinol-9 + fumarate + H+ <=> menaquinone-9(2H) + H+ + succinate 1.3.5.1 succinate dehydrogenase

menaquinol-9 + fumarate + H+ <=> menaquinone-9(2H) + H+ + succinate 1.3.5.4 fumarate reductase (quinol)

L-glutamate + 2-oxoglutarate + O2 <=> threo-beta-Hydroxy-DL-glutamate + succinate + CO2 1.14.11.ax

M
(11S,16S)-ent-kauran-11,16-epoxy-19-oate + 2-oxoglutarate + O2 <=> (7S,11S,16S)-7-hydroxy-ent-kauran-11,16-epoxy-19-oate + succinate + CO2 1.14.11

M
gibberellin_A34 + 2-oxoglutarate + O2 <=> H+ + Gibberellin_A34-catabolite + succinate + CO2 + H2O 1.14.20

M
Leucocyanidin + 2-oxoglutarate + O2 <=> (4S)-2,3-dehydro-leucocyanidin + succinate + CO2 + H2O 1.14.20.4 anthocyanidin synthase

H+ + gibberellin_44 + 2-oxoglutarate + O2 <=> gibberellin_a38 + succinate + CO2 + H2O 1.14.20

M
gibberellin_A25 + 2-oxoglutarate + O2 <=> gibberellin_A13 + succinate + CO2 1.14.11

M
gibberellin_A13 + 2-oxoglutarate + O2 <=> gibberellin_A43 + succinate + CO2 1.14.11

gibberellin_A25 + 2-oxoglutarate + O2 <=> gibberellin_A46 + succinate + CO2 1.14.11

gibberellin_A12 + 2-oxoglutarate + O2 <=> Gibberellin_A14 + succinate + CO2 1.14.11

M
gibberellin_A17 + 2-oxoglutarate + O2 <=> gibberellin_A28 + succinate + CO2 1.14.11

gibberellin_A28 + 2-oxoglutarate + O2 <=> (2betaOH)-gibberellin28 + succinate + CO2 1.14.11

Gibberellin_A14 + O2 + 2-oxoglutarate <=> gibberellin_a37 + CO2 + succinate 1.14.11

M
gibberellin_a37 + 2-oxoglutarate + O2 <=> Gibberellin_A36 + succinate + CO2 + H2O 1.14.20

M
Gibberellin_A36 + O2 + 2-oxoglutarate + NADP+ <=> gibberellin_a4 + succinate + CO2 + NADPH 1.14.11

M
[protein]_N6,N6-dimethyl-L-lysine + 2-oxoglutarate + O2 <=> [protein]_N6-methyl-L-lysine + succinate + formaldehyde + CO2 not assigned

[protein]_N6-methyl-L-lysine + 2-oxoglutarate + O2 <=> a_[protein]-L-tyrosine + succinate + formaldehyde + CO2 1.14.11

H+ + gibberellin_44 + 2-oxoglutarate + O2 <=> gibberellin_A98 + succinate + CO2 1.14.11

M
(3-methylbenzyl)succinic_acid + succinyl-CoA <=> (3-methylbenzyl)succinyl-CoA + succinate not assigned

M
gibberellin_A12 + 2-oxoglutarate + O2 <=> gibberellin_A110 + succinate + CO2 1.14.11

M
4-chloro-2-methylphenoxyacetate + 2-oxoglutarate + O2 <=> 4-chloro-2-methylphenol + glyoxylate + succinate + CO2 1.14.11

M
2-chloro-4-methyl-phenoxyacetate + 2-oxoglutarate + O2 <=> 2-chloro-4-methylphenol + glyoxylate + succinate + CO2 1.14.11

Gibberellin_A53 + 2-oxoglutarate + O2 <=> gibberellin_A97 + succinate + CO2 1.14.11

M
fumarate + H+ + e- <=> succinate not assigned

[50S_ribosomal_subunit_protein_L16]-L-arginine81 + 2-oxoglutarate + O2 <=> [50S_ribosomal_subunit_protein_L16]-(3R)-3-hydroxy-L-arginine81 + succinate + CO2 1.14.11.47 [50S ribosomal protein L16]-arginine 3-hydroxylase

1,N6-ethenoadenine_in_DNA + 2-oxoglutarate + O2 + H2O <=> adenine_in_DNA + Glyoxal + succinate + CO2 not assigned

N1-ethyladenine_in_DNA + 2-oxoglutarate + O2 <=> adenine_in_DNA + acetaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

22,26-dihydroxycholesterol + 2-oxoglutarate + O2 <=> 16alpha,22,26-trihydroxycholesterol + succinate + CO2 1.14.11

M
Gibberellin_19 + O2 + 2-oxoglutarate <=> H+ + gibberellin_A17 + succinate + CO2 1.14.11

M
Gibberellin_A24 + O2 + 2-oxoglutarate <=> H+ + gibberellin_a9 + CO2 + succinate 1.14.11

M
Gibberellin_A24 + O2 + 2-oxoglutarate <=> H+ + gibberellin_A25 + CO2 + succinate 1.14.11

M
succinate + plastoquinone <=> fumarate + plastoquinol 1.3.5.1 succinate dehydrogenase

fumarate + H+ + e- <=> succinate not assigned

3-methyl-branched_2,3,4-saturated_fatty_acyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxy-3-methyl-branched_2,3,4-saturated_fatty_acyl-CoA + succinate + CO2 1.14.11

M
ubiquinone-6 + succinate <=> ubiquinol-6 + fumarate 1.3.5.1 succinate dehydrogenase

succinate + fumarate <=> fumarate + succinate not assigned

succinate + L-aspartate <=> L-aspartate + succinate not assigned

succinate + (S)-malate <=> (S)-malate + succinate not assigned

H+ + succinate <=> H+ + succinate not assigned

L-Tartrate + succinate <=> L-Tartrate + succinate not assigned

succinate + H+ <=> succinate + H+ not assigned

succinate + citrate <=> citrate + succinate not assigned

(S,S)-Tartrate + succinate <=> succinate + (S,S)-Tartrate not assigned

dihydroquercetin + 2-oxoglutarate + O2 <=> quercetin + succinate + O2 1.14.20.4 anthocyanidin synthase

taxifolin + 2-oxoglutarate + O2 <=> quercetin + succinate + O2 1.14.20.4 anthocyanidin synthase

naringenin + 2-oxoglutarate + O2 <=> dihydrokaempferol + succinate + O2 1.14.20.4 anthocyanidin synthase

2-thienylmethylpenicillin + 2-oxoglutarate + O2 <=> (6R,7R)-3-methyl-8-oxo-7-[(thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

(3R,5R)-carbapenam-3-carboxylate + 2-oxoglutarate + O2 <=> (5R)-carbapen-2-em-3-carboxylate + succinate + CO2 + H2O 1.14.20.3 (5R)-carbapenem-3-carboxylate synthase

(3R,5S)-carbapenam-3-carboxylate + 2-oxoglutarate + O2 <=> (5R)-carbapen-2-em-3-carboxylate + succinate + CO2 + H2O 1.14.20.3 (5R)-carbapenem-3-carboxylate synthase

t-cinnamoyltropine + 2-oxoglutarate + O2 <=> t-cinnamoyl-6-hydroxytropine + succinate + CO2 + H2O 1.14.20.13 6beta-hydroxyhyoscyamine epoxidase

(L-Pro-trans-4-hydroxy-L-Pro-Gly)5 + 2-oxoglutarate + O2 <=> (trans-3-hydroxy-L-Pro-trans-4-hydroxy-L-Pro-Gly)5 + succinate + CO2 1.14.11.7 procollagen-proline 3-dioxygenase

L-Leu-L-Asn-Gly-L-Leu-L-4Hyp-Gly-L-Pro-L-Ile-Gly-L-Pro-L-4Hyp-Gly-L-Pro-L-Arg-Gly-L-Arg-L-Thr-Gly-L-Asp-L-Ala-Gly + 2-oxoglutarate + O2 <=> L-Leu-L-Asn-Gly-L-Leu-L-4Hyp-Gly-trans-3-hydroxy-L-Pro-L-Ile-Gly-L-Pro-L-4Hyp-Gly-trans-3-hydroxy-L-Pro-L-Arg-Gly-L-Arg-L-Thr-Gly-L-Asp-L-Ala-Gly + succinate + CO2 1.14.11.7 procollagen-proline 3-dioxygenase

gibberellin_a9 + 2-oxoglutarate + O2 <=> gibberellin_a5 + succinate + CO2 1.14.11.15 gibberellin 3beta-dioxygenase

gibberellin_a20 + 2-oxoglutarate + O2 <=> gibberellin_a5 + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

eriodyctiol + 2-oxoglutarate + O2 <=> dihydroquercetin + succinate + CO2 1.14.11.9 flavanone 3-dioxygenase

naringenin + 2-oxoglutarate + O2 <=> dihydroquercetin + succinate + CO2 1.14.11.9 flavanone 3-dioxygenase

(Gly-L-Pro-L-4-hydroxyproline)5 + 2-oxoglutarate + O2 <=> Gly-trans-3-hydroxy-L-Pro-trans-4-hydrox-L-Pro)5 + succinate + CO2 1.14.11.7 procollagen-proline 3-dioxygenase

L-Ala-(L-Pro)4-Gly-L-Ile-L-Pro-Gly-L-Tyr-(L-Pro)2-L-Ala-(L-Pro)4-Gly-L-Val-Gly-(L-Pro)4-L-Gln-Gly_L-proline + 2-oxoglutarate + O2 <=> L-Ala-(L-Pro)4-Gly-L-Ile-L-Pro-Gly-L-Tyr-(L-Pro)2-L-Ala-(L-Pro)4-Gly-L-Val-Gly-(L-Pro)4-L-Gln-Gly_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

L-Pro-L-Ile-(L-Pro)7-L-Leu-L-Pro-L-Gln-L-Asn-L-Leu-L-Ser-Gly-L-Ala-L-Pro_L-proline + 2-oxoglutarate + O2 <=> L-Pro-L-Ile-(L-Pro)7-L-Leu-L-Pro-L-Gln-L-Asn-L-Leu-L-Ser-Gly-L-Ala-L-Pro_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

L-homoarginine + 2-oxoglutarate + O2 <=> (3S)-N6-(diaminomethylidene)-3-hydroxy-L-lysine + succinate + CO2 1.14.11.41 L-arginine hydroxylase

L-norleucine + 2-oxoglutarate + O2 <=> 4-hydroxy-L-norleucine + succinate + CO2 1.14.11.45 L-isoleucine 4-hydroxylase

L-ethionine + 2-oxoglutarate + O2 <=> L-ethionine_(S)-sulfoxide + succinate + CO2 1.14.11.45 L-isoleucine 4-hydroxylase

L-ethionine + 2-oxoglutarate + O2 <=> L-ethionine_sulfoxide + succinate + CO2 1.14.11.45 L-isoleucine 4-hydroxylase

S-allyl-L-cysteine + 2-oxoglutarate + O2 <=> S-allyl-L-cysteine_(S)-sulfoxide + succinate + CO2 1.14.11.45 L-isoleucine 4-hydroxylase

AVSEATIR + 2-oxoglutarate + O2 <=> [AVSEATIR]-(3R)-3-hydroxy-L-Arg8 + succinate + CO2 1.14.11.47 [50S ribosomal protein L16]-arginine 3-hydroxylase

KPITEKPLAVRMGKGKGNVE + 2-oxoglutarate + O2 <=> [KPITEKPLAVRMGKGKGNVE]-(3R)-3-hydroxy-L-Arg11 + succinate + CO2 1.14.11.47 [50S ribosomal protein L16]-arginine 3-hydroxylase

RLLPAVSEATIRRL + 2-oxoglutarate + O2 <=> [RLLPAVSEATIRRL]-(3R)-3-hydroxy-L-Arg12 + succinate + CO2 1.14.11.47 [50S ribosomal protein L16]-arginine 3-hydroxylase

hypoxia-inducible_factor-L-proline + 2-oxoglutarate + O2 <=> hypoxia-inducible_factor-(4R)-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase
1.14.11.29 hypoxia-inducible factor-proline dioxygenase
1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase



hypoxia-inducible_factor1alpha_C-terminal_oxygen-dependent_degradation_domain-L-proline + 2-oxoglutarate + O2 <=> hypoxia-inducible_factor-(4R)-4-hydroxy-L-proline + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

d(Tpm1A) + 2-oxoglutarate + O2 <=> d(TpA) + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

d(Tpm1ApT) + 2-oxoglutarate + O2 <=> d(TpApT) + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

methylated_tRNA-Phe + 2-oxoglutarate + O2 <=> tRNAMet + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

5''-CUCGAUACG(m6A)UCCGGUCAAA-3'' + 2-oxoglutarate + O2 <=> 5''-CUCGAUACGAUCCGGUCAAA-3'' + formaldehyde + succinate + CO2 1.14.11.53 mRNA N6-methyladenine demethylase

GA(m6A)CA + 2-oxoglutarate + O2 <=> GAACA + formaldehyde + succinate + CO2 1.14.11.53 mRNA N6-methyladenine demethylase

GG(m6A)CU + 2-oxoglutarate + O2 <=> GGACU + formaldehyde + succinate + CO2 1.14.11.53 mRNA N6-methyladenine demethylase

1-methyl-adenine_in_5''-dAAAA-1MeA-YYAAA + 2-oxoglutarate + O2 <=> 5''-dAAAAAYYAAA + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

6-Methylaminopurine + 2-oxoglutarate + O2 <=> adenine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

ATKAARK(me3)-SAPATGGVKKPHRYRPG-GK(biotin) + 2-oxoglutarate + O2 <=> ATKAARKSAPATGGVKKPHRYRPG-GK(biotin) + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase


S:_[histone_H3]-N6,N6,N6-trimethyl-L-lysine9 + 2-oxoglutarate + O2 <=> histone_H3_N6,N6-dimethyl-L-lysine9 + succinate + formaldehyde + CO2 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase

[histone_H3]-N6,N6-dimethyl-L-lysine4 + 2-oxoglutarate + O2 <=> [histone_H3]-L-lysine4 + succinate + formaldehyde + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase
1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase





[histone_H3]-N6,N6-methyl-L-lysine4 + 2-oxoglutarate + O2 <=> [histone_H3]-L-lysine4 + succinate + formaldehyde + CO2 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase

[histone-H3]-tridimethyllysine4 + 2 2-oxoglutarate + 2 O2 <=> [histone_H3]-N6-methyl-L-lysine4 + 2 succinate + 2 formaldehyde + 2 CO2 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase

[histone_H3]-N6,N6-drimethyl-L-lysine_4 + 2-oxoglutarate + O2 <=> [histone_H3]-N6-methyl-L-lysine-4 + succinate + formaldehyde + CO2 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase

histone_H3_N6,N6,N6-trimethyl-L-lysine9 + 2-oxoglutarate + O2 <=> [histone_H3]-L-lysine9 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

histone_H3_N6,N6-dimethyl-L-lysine36 + 2-oxoglutarate + O2 <=> methyl-histone_3_lysine_9 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

dimethyl-histone_3_L-lysine_36 + 2-oxoglutarate + O2 <=> histone_H3_N6-methyl-L-lysine36 + succinate + formaldehyde + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase


histone_H4_N6-methyl-L-lysine20 + 2-oxoglutarate + O2 <=> histone_H4(K20) + succinate + formaldehyde + CO2 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase

protein_6-N,6-N-dimethyl-L-lysine + 2-oxoglutarate + O2 <=> protein_N6-methyl-L-lysine + succinate + formaldehyde + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase


protein_N6-methyl-L-lysine + 2-oxoglutarate + O2 <=> a_[protein]-L-tyrosine + succinate + formaldehyde + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase


single-stranded_DNA-3-methylcytosine + 2-oxoglutarate + O2 <=> DNA-cytosine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

double-stranded_DNA-3-methylcytosine + 2-oxoglutarate + O2 <=> DNA-cytosine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

DNA-3-methylcytosine + 2-oxoglutarate + O2 <=> DNA-cytosine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

DNA-1-methylcytosine-CH3 + 2-oxoglutarate + O2 <=> DNA-cytosine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

2''-deoxy-1-methyl-adenosine_3''-phosphate + 2-oxoglutarate + O2 <=> 2''-deoxyadenosine_3''-phosphate + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

tRNA-1-methylguanine + 2-oxoglutarate + O2 <=> tRNA + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

1-methylthymine + 2-oxoglutarate + O2 <=> 1-methyl-5-(hydroxymethyl)uracil + thymine + formaldehyde + succinate + CO2 1.14.11.6 thymine dioxygenase

3-methylcytosine + O2 + 2-oxoglutarate <=> cytosine + CO2 + formaldehyde + succinate + H+ 1.14.11.33 DNA oxidative demethylase

N3-methylcytosine + 2-oxoglutarate + O2 <=> cytosine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

thebaine + 2-oxoglutarate + O2 <=> codeinone + formaldehyde + succinate + CO2 1.14.11.31 thebaine 6-O-demethylase

trimethyl-histone_3_L-lysine_36 + 2-oxoglutarate + O2 <=> dimethyl-histone_3_L-lysine_36 + succinate + formaldehyde + CO2 1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase

[histone_H3_peptide_21mer]-N6-methyl-L-lysine4 + 2-oxoglutarate + O2 <=> [histone_H3_peptide_21mer]-L-lysine4 + succinate + formaldehyde + CO2 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase

[histone_H3_peptide_21mer]-N6,N6-dimethyl-L-lysine4 + 2-oxoglutarate + O2 <=> [histone_H3_peptide_21mer]-L-lysine4 + succinate + formaldehyde + CO2 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase

single-stranded_DNA-1-methyladenine + 2-oxoglutarate + O2 <=> DNA_adenine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

double-stranded_DNA-1-methyladenine + 2-oxoglutarate + O2 <=> DNA_adenine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

DNA-1,N6-ethenoadenine + 2-oxoglutarate + O2 <=> DNA_adenine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

DNA-1-methyladenine + 2-oxoglutarate + O2 <=> DNA_adenine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

DNA-N1-methyladenine + 2-oxoglutarate + O2 <=> DNA_adenine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

[protein_p53]-N6,N6-dimethyl-L-lysine370 + 2-oxoglutarate + O2 <=> [protein_p53]-L-lysine370 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

[protein_p53]-N6-methyl-L-lysine370 + 2-oxoglutarate + O2 <=> [protein_p53]-L-lysine370 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

DNA-base-CH3 + 2-oxoglutarate + O2 <=> DNA-base + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

[histone-H3]-tridimethyllysine4 + 2-oxoglutarate + O2 <=> histone_H3_N6,N6-dimethyl-L-lysine4 + succinate + formaldehyde + CO2 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase

histone_H3_N6,N6-dimethyl-L-lysine4 + 2-oxoglutarate + O2 <=> histone_H3_N6-methyl-L-lysine4 + succinate + formaldehyde + CO2 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase
1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase


methylated_poly(deoxyadenine) + 2-oxoglutarate + O2 <=> poly(deoxyadenine) + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

N3-methylcytosine_in_single-stranded_DNA + 2-oxoglutarate + O2 <=> cytosine_in_single-stranded_DNA + formaldehyde + succinate + CO2 1.14.11.53 mRNA N6-methyladenine demethylase

[histone_H3_peptide_21mer]-N6-methyl-L-lysine4-acetyl-L-lysine9 + 2-oxoglutarate + O2 <=> [histone_H3_peptide_21mer]-L-lysine4-acetyl-L-lysine9 + succinate + formaldehyde + CO2 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase

[histone_H3_peptide_30mer]-N6-methyl-L-lysine4 + 2-oxoglutarate + O2 <=> [histone_H3_peptide_30mer]-L-lysine4 + succinate + formaldehyde + CO2 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase

[histone_H3]-N6,N6-dimethyl-L-lysine4 + 2-oxoglutarate + O2 <=> histone_H3_L-lysine4 + succinate + formaldehyde + CO2 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase

histone_H3_N6-methyl-L-lysine4 + 2-oxoglutarate + O2 <=> histone_H3_L-lysine4 + succinate + formaldehyde + CO2 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase
1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase


methylated_DNA_bacteriophage_M13mp18 + 2-oxoglutarate + O2 <=> DNA_bacteriophage_M13mp18 + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

DNA-1-methylguanine + 2-oxoglutarate + O2 <=> DNA_guanine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

DNA-3-methylthymine + 2-oxoglutarate + O2 <=> DNA-thymine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

methylated_double-stranded_bacteriophage_lambda + 2-oxoglutarate + O2 <=> double-stranded_bacteriophage_lambda + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

double-stranded_DNA-3-methylcytosine + 2-oxoglutarate + O2 <=> double-stranded_DNA-cytosine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

methylated_luciferase-mRNA + 2-oxoglutarate + O2 <=> luciferase-mRNA + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

methylated_poly(deoxycytosine) + 2-oxoglutarate + O2 <=> poly(deoxycytosine) + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

methylated_poly(deoxythymine) + 2-oxoglutarate + O2 <=> poly(deoxythymine) + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

methylated_RNA_bacteriophage_MS2 + 2-oxoglutarate + O2 <=> RNA_bacteriophage_MS2 + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

RNA-1-methyladenine + 2-oxoglutarate + O2 <=> RNA-adenine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

RNA-N1-methyladenine + 2-oxoglutarate + O2 <=> RNA-adenine + formaldehyde + succinate + CO2 1.14.11.54 mRNA N1-methyladenine demethylase

RNA-N6-methyladenine + 2-oxoglutarate + O2 <=> RNA-adenine + formaldehyde + succinate + CO2 1.14.11.54 mRNA N1-methyladenine demethylase

RNA-3-methylcytosine + 2-oxoglutarate + O2 <=> RNA-cytosine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

single-stranded_DNA-3-methylcytosine + 2-oxoglutarate + O2 <=> single-stranded_DNA-cytosine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

methylated_single-stranded_poly(deoxyadenosine) + 2-oxoglutarate + O2 <=> single-stranded_poly(deoxyadenosine) + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

N3-methylthymine_in_single-stranded_DNA + 2-oxoglutarate + O2 <=> thymine_in_single-stranded_DNA + formaldehyde + succinate + CO2 1.14.11.53 mRNA N6-methyladenine demethylase

protein_C/EBPalpha-N6,N6-dimethyl-L-lysine + 2-oxoglutarate + O2 <=> protein_C/EBPalpha-N6-methyl-L-lysine + succinate + formaldehyde + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase

RNA-base-CH3 + 2-oxoglutarate + O2 <=> RNA-base + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

N3-methyluracil_in_single-stranded_mRNA + 2-oxoglutarate + O2 <=> uracil_in_single-stranded_mRNA + formaldehyde + succinate + CO2 1.14.11.53 mRNA N6-methyladenine demethylase

5''-UACACUCGAUCUGG(m6A)CUAAAGCUGCUC-3''-biotin + 2-oxoglutarate + O2 <=> 5''-UACACUCGAUCUGGCUAAAGCUGCUC-3''-biotin + formaldehyde + succinate + CO2 1.14.11.53 mRNA N6-methyladenine demethylase

N6-methyladenine_in_NANOG_mRNA + 2-oxoglutarate + O2 <=> adenine_in_NANOG_mRNA + formaldehyde + succinate + CO2 1.14.11.53 mRNA N6-methyladenine demethylase

N6-methyladenine_in_single-stranded_DNA + 2-oxoglutarate + O2 <=> adenine_in_single-stranded_DNA + formaldehyde + succinate + CO2 1.14.11.53 mRNA N6-methyladenine demethylase

N6-methyladenine_in_single-stranded_DNA_oligonucleotide + 2-oxoglutarate + O2 <=> adenine_in_single-stranded_DNA_oligonucleotide + formaldehyde + succinate + CO2 1.14.11.53 mRNA N6-methyladenine demethylase

GCGG(m6A)CUCCAGAUG + 2-oxoglutarate + O2 <=> GCGGACUCCAGAUG + formaldehyde + succinate + CO2 1.14.11.53 mRNA N6-methyladenine demethylase

N1-methylguanine_in_DNA + 2-oxoglutarate + O2 <=> DNA_guanine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

N3-methylthymine_in_DNA + 2-oxoglutarate + O2 <=> thymine_in_DNA + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

5''-dAAAA-1-methyladenine-AYYAAA + 2-oxoglutarate + O2 <=> 5''-dAAAA-adenine-AYYAAA + formaldehyde + succinate + CO2 1.14.11.54 mRNA N1-methyladenine demethylase

N1-methyladenine_in_ssDNA + 2-oxoglutarate + O2 <=> adenine_in_ssDNA + formaldehyde + succinate + CO2 1.14.11.54 mRNA N1-methyladenine demethylase

DNA-1-methyldeoxyadenine + 2-oxoglutarate + O2 <=> DNA-deoxyadenine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

DNA-2-methylguanosine + 2-oxoglutarate + O2 <=> DNA-guanosine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

oripavine + 2-oxoglutarate + O2 <=> morphinane + formaldehyde + succinate + CO2 1.14.11.31 thebaine 6-O-demethylase

neopine + 2-oxoglutarate + O2 <=> neomorphine + formaldehyde + succinate + CO2 1.14.11.32 codeine 3-O-demethylase

H3(1-20)_K4-dimethylated_peptide + 2-oxoglutarate + O2 <=> H3(1-20)_K4-monomethylated_peptide + succinate + formaldehyde + CO2 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase

H31-15K9me3 + 2-oxoglutarate + O2 <=> H31-15K9me2 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

[histone_H3]-N6,N6,N6-trimethyl-L-lysine36 + 2-oxoglutarate + O2 <=> histone_H3_N6,N6-dimethyl-L-lysine26 + succinate + formaldehyde + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase

histone_H3_N6,N6,N6-trimethyl-L-lysine26 + 2-oxoglutarate + O2 <=> histone_H3_N6,N6-dimethyl-L-lysine26 + succinate + formaldehyde + CO2 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase

histone_H3_N6,N6-dimethyl-L-lysine27 + 2-oxoglutarate + O2 <=> histone_H3_N6-methyl-L-lysine27 + succinate + formaldehyde + CO2 1.14.18.B1

poly(dm1A) + 2-oxoglutarate + O2 <=> poly(dA) + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

a_[histone_H3]-N6,N6,N6-trimethyl-L-lysine56 + 3 2-oxoglutarate + 3 O2 <=> a_[histone_H3]-L-lysine56 + 3 succinate + 3 formaldehyde + 3 CO2 1.14.11.B19

a_[histone_H3]-N6,N6,N6-trimethyl-L-lysine56 + 2-oxoglutarate + O2 <=> a_[histone_H3]-N6,N6-dimethyl-L-lysine56 + succinate + formaldehyde + CO2 1.14.11.B19

a_[histone_H3]-N6,N6-dimethyl-L-lysine56 + 2-oxoglutarate + O2 <=> a_[histone_H3]-N6-methyl-L-lysine56 + succinate + formaldehyde + CO2 1.14.11.B19

a_[histine_H3]-N6,N6,N6-trimethyllysine27 + 2 2-oxoglutarate + 2 O2 <=> a_[histine_H3]-N6-methyllysine27 + 2 succinate + 2 formaldehyde + 2 CO2 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase

CDYL1-K135me3 + 2-oxoglutarate + O2 <=> CDYL1-K135me2 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

CSB-K1054me3 + 2-oxoglutarate + O2 <=> CSB-K1054me2 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

CSB-K170me3 + 2-oxoglutarate + O2 <=> CSB-K170me2 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

CSB-K297me3 + 2-oxoglutarate + O2 <=> CSB-K297me2 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

CSB-K448me3 + 2-oxoglutarate + O2 <=> CSB-K448me2 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

G9a-K185me3 + 2-oxoglutarate + O2 <=> G9a-K185me2 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

H3K4me2_(1-21_aa)_peptide + 2-oxoglutarate + O2 <=> H3K4me1_(1-21_aa)_peptide + succinate + formaldehyde + CO2 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase

H3K4me2_1-21_peptide + 2-oxoglutarate + O2 <=> H3K4me1_1-21_peptide + succinate + formaldehyde + CO2 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase

H3K4me2_peptide_3-21 + 2-oxoglutarate + O2 <=> H3K4me1_peptide_3-21 + succinate + formaldehyde + CO2 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase

WIZ-K305me3 + 2-oxoglutarate + O2 <=> WIZ-K305me2 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

[histone_H3,_A7H]-N6,N6,N6-trimethyl-L-lysine_9 + 2-oxoglutarate + O2 <=> [histone_H3,_A7H]-N6,N6-dimethyl-L-lysine_9 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

[histone_H3,_A7R]-N6,N6,N6-trimethyl-L-lysine_9 + 2-oxoglutarate + O2 <=> [histone_H3,_A7R]-N6,N6-dimethyl-L-lysine_9 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

[histone_H3,_G12P]-N6,N6,N6-trimethyl-L-lysine_9 + 2-oxoglutarate + O2 <=> [histone_H3,_G12P]-N6,N6-dimethyl-L-lysine_9 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

[histone_H3]-N6-methyllysine27 + 2-oxoglutarate + O2 <=> [histone_H3]-lysine27 + succinate + formaldehyde + CO2 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase

[histone_H3]-N6,N6,N6-trimethyllysine36 + 2 2-oxoglutarate + 2 O2 <=> [histone_H3]-lysine36 + 2 succinate + 2 formaldehyde + 2 CO2 1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase

[histone_H3]-N6,N6-dimethyllysine36 + 2-oxoglutarate + O2 <=> [histone_H3]-lysine36 + succinate + formaldehyde + CO2 1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase

[histone_H3]-N6,N6,N6-trimethyl-L-lysine_26 + 2-oxoglutarate + O2 <=> [histone_H3]-N6,N6-dimethyl-L-lysine_26 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase


[histone_H3]-N6,N6,N6-trimethyl-L-lysine_26 + 2-oxoglutarate + O2 <=> [histone_H3]-N6,N6-dimethyl-L-lysine26 + succinate + formaldehyde + CO2 1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase

[histone_H3]-N6,N6,N6-trimethyl-L-lysine56 + 2-oxoglutarate + O2 <=> [histone_H3]-N6,N6-dimethyl-L-lysine56 + succinate + formaldehyde + CO2 1.14.11.B19

[histone_H3]-N6,N6,N6-trimethyllysine27 + 2-oxoglutarate + O2 <=> [histone_H3]-N6,N6-dimethyllysine27 + succinate + formaldehyde + CO2 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase

[histone_H3]-N6,N6,N6-trimethyllysine36 + 2-oxoglutarate + O2 <=> [histone_H3]-N6,N6-dimethyllysine36 + succinate + formaldehyde + CO2 1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase

[histone_H3]-N6,N6,N6-trimethyl-L-lysine56 + 2 2-oxoglutarate + 2 O2 <=> [histone_H3]-N6-methyl-L-lysine56 + 2 succinate + 2 formaldehyde + 2 CO2 1.14.11.B19

[histone_H3]-N6,N6-dimethyl-L-lysine56 + 2-oxoglutarate + O2 <=> [histone_H3]-N6-methyl-L-lysine56 + succinate + formaldehyde + CO2 1.14.11.B19

[histone_H3]-N6,N6,N6-trimethyllysine27 + 2 2-oxoglutarate + 2 O2 <=> [histone_H3]-N6-methyllysine27 + 2 succinate + 2 formaldehyde + 2 CO2 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase

[histone_H3]-N6,N6-dimethyllysine27 + 2-oxoglutarate + O2 <=> [histone_H3]-N6-methyllysine27 + succinate + formaldehyde + CO2 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase

[histone_H3]-N6,N6,N6-trimethyllysine36 + 2 2-oxoglutarate + 2 O2 <=> [histone_H3]-N6-methyllysine36 + 2 succinate + 2 formaldehyde + 2 CO2 1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase

[histone_H3]-N6,N6-dimethyllysine36 + 2-oxoglutarate + O2 <=> [histone_H3]-N6-methyllysine36 + succinate + formaldehyde + CO2 1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase

[acetylated_histone_H3_21mer]-N6,N6,N6-trimethyl-L-lysine4 + 2-oxoglutarate + O2 <=> [acetylated_histone_H3_21mer]-N6,N6-dimethyl-L-lysine4 + succinate + formaldehyde + CO2 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase

double-stranded_DNA-1-methyladenine + 2-oxoglutarate + O2 <=> double-stranded_DNA-adenine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

single-stranded_DNA-1-methyladenine + 2-oxoglutarate + O2 <=> single-stranded_DNA-adenine + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

ARTK(me3)QTARKS + 2-oxoglutarate + O2 <=> ARTK(me2)QTARKS + succinate + formaldehyde + CO2 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase

[acetylated_histone_H3_21mer]-N6,N6-dimethyl-L-lysine4 + 2-oxoglutarate + O2 <=> [acetylated_histone_H3_21mer]-N6-methyl-L-lysine4 + succinate + formaldehyde + CO2 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase

[polycomb_2_protein]-N6,N6-dimethyl-L-lysine191 + 2-oxoglutarate + O2 <=> [polycomb_2_protein]-N6-methyl-L-lysine191 + succinate + formaldehyde + CO2 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase

scoulerine + 2-oxoglutarate + O2 <=> 3-O-demethylscoulerine + formaldehyde + succinate + CO2 1.14.11.32 codeine 3-O-demethylase

dansyl-Gly-Phe-Pro-Gly-OEt + 2-oxoglutarate + O2 <=> dansyl-Gly-Phe-4-hydroxy-L-Pro-Gly-OEt + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(2S,3R,4S)-4-hydroxy-isoleucine + 2-oxoglutarate + O2 <=> (2S,3R)-2-amino-3-methyl-4-ketopentanoate + succinate + CO2 1.14.11.45 L-isoleucine 4-hydroxylase

L-allo-isoleucine + 2-oxoglutarate + O2 <=> (S)-3-hydroxy-L-allo-isoleucine + succinate + CO2 1.14.11.45 L-isoleucine 4-hydroxylase

L-norvaline + 2-oxoglutarate + O2 <=> (S)-4-hydroxy-L-norvaline + succinate + CO2 1.14.11.45 L-isoleucine 4-hydroxylase

(4S)-ectoine + 2-oxoglutarate + O2 <=> 5-hydroxyectoine + succinate + CO2 1.14.11.55 ectoine hydroxylase

gibberellin_44 + 2-oxoglutarate + O2 <=> gibberellin_98 + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

(2R,3S,4R)-leucocyanidin + 2-oxoglutarate + O2 <=> taxifolin + cis-dihydroquercetin + quercetin + succinate + CO2 1.14.20.4 anthocyanidin synthase

Leucocyanidin + 2-oxoglutarate + O2 <=> quercetin + succinate + CO2 1.14.20.4 anthocyanidin synthase

N5,N5,N5-trimethyl-L-ornithine + 2-oxoglutarate + O2 <=> (3S)-3-hydroxy-N5,N5,N5-trimethyl-L-ornithine + succinate + CO2 1.14.11.8 trimethyllysine dioxygenase

a_flavanone + 2-oxoglutarate + O2 <=> a_dihydroflavonol + succinate + CO2 1.14.11.9 flavanone 3-dioxygenase

3-aminoisobutanoate + 2-oxoglutarate + O2 <=> 3-amino-2-hydroxy-2-methylpropanoic_acid + succinate + CO2 1.14.11.17 taurine dioxygenase

3-carboxy-N-(fluoromethyl)-N,N-dimethylpropan-1-aminium + 2-oxoglutarate + O2 <=> (2S)-3-carboxy-N-(fluoromethyl)-2-hydroxy-N,N-dimethylpropan-1-aminium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

[(2R)-3-carboxy-2-hydroxypropyl](trimethyl)arsanium + 2-oxoglutarate + O2 <=> (3-carboxy-2-oxopropyl)(trimethyl)arsanium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

[(2S)-3-carboxy-2-hydroxypropyl](trimethyl)arsanium + 2-oxoglutarate + O2 <=> (3-carboxy-2-oxopropyl)(trimethyl)arsanium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

[(2R)-3-carboxy-2-hydroxypropyl](trimethyl)phosphanium + 2-oxoglutarate + O2 <=> (3-carboxy-2-oxopropyl)(trimethyl)phosphanium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

[(2S)-3-carboxy-2-hydroxypropyl](trimethyl)phosphanium + 2-oxoglutarate + O2 <=> (3-carboxy-2-oxopropyl)(trimethyl)phosphanium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

D-carnitine + 2-oxoglutarate + O2 <=> (3S)-3-carboxy-2,3-dihydroxy-N,N,N-trimethylpropan-1-aminium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

3-Trimethylaminopropionic_acid + 2-oxoglutarate + O2 <=> 2-carboxy-2-hydroxy-N,N,N-trimethylethan-1-aminium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

N,N,N-trimethyl-4-aminobutanoate + 2-oxoglutarate + O2 <=> 4-carboxy-3-hydroxy-N,N,N-trimethylbutan-1-aminium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

gamma-butyrobetaine + 2-oxoglutarate + O2 <=> 4-carboxy-3-hydroxy-N,N,N-trimethylbutan-1-aminium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

L-aminocarnitine + 2-oxoglutarate + O2 <=> N-[(3R)-3-amino-3-carboxy-2-hydroxypropyl]-N,N-dimethylmethanaminium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

L-aminocarnitine + 2-oxoglutarate + O2 <=> N-[(3S)-3-amino-3-carboxy-2-hydroxypropyl]-N,N-dimethylmethanaminium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

(3-carboxypropyl)(trimethyl)arsanium + 2-oxoglutarate + O2 <=> [(2R)-3-carboxy-2-hydroxypropyl](trimethyl)arsanium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

(3-carboxypropyl)(trimethyl)phosphanium + 2-oxoglutarate + O2 <=> [(2R)-3-carboxy-2-hydroxypropyl](trimethyl)phosphanium + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

N6,N6-dimethyl-N6-ethyl-L-lysine + 2-oxoglutarate + O2 <=> (3S)-3-hydroxy-N6,N6-dimethyl-N6-ethyl-L-lysine + succinate + CO2 1.14.11.8 trimethyllysine dioxygenase

N6,N6-dimethyl-N6-isopropyl-L-lysine + 2-oxoglutarate + O2 <=> (3S)-3-hydroxy-N6,N6-dimethyl-N6-isopropyl-L-lysine + succinate + CO2 1.14.11.8 trimethyllysine dioxygenase

N6,N6-dimethyl-N6-propyl-L-lysine + 2-oxoglutarate + O2 <=> (3S)-3-hydroxy-N6,N6-dimethyl-N6-propyl-L-lysine + succinate + CO2 1.14.11.8 trimethyllysine dioxygenase

N6-fluoromethyl-N6,N6-dimethyl-L-lysine + 2-oxoglutarate + O2 <=> (3S)-3-hydroxy-N6-fluoromethyl-N6,N6-dimethyl-L-lysine + succinate + CO2 1.14.11.8 trimethyllysine dioxygenase

N7,N7,N7-trimethyl-L-alpha-homolysine + 2-oxoglutarate + O2 <=> (3S)-3-hydroxy-N7,N7,N7-trimethyl-L-alpha-homolysine + succinate + CO2 1.14.11.8 trimethyllysine dioxygenase

cephalosporin_G + 2-oxoglutarate + O2 <=> deacetylcephalosporin_G + succinate + CO2 1.14.11.26 deacetoxycephalosporin-C hydroxylase

mannan-binding_lectin-A-L-lysine + 2-oxoglutarate + O2 <=> mannan-binding_lectin-A-5-hydroxy-L-lysine + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

protein_L-lysine + 2-oxoglutarate + O2 <=> [procollagen]-(2S,5R)-5-hydroxy-L-lysine + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

12-epi-fischerindole_U + 2-oxoglutarate + O2 + Br- <=> 13R-bromo-12-epi-fischerindole_U + succinate + CO2 + H2O 1.14.20.14 hapalindole-type alkaloid chlorinase

Argonaute_2 + 2-oxoglutarate + O2 <=> 4-hydroxyproline-Argonaute_2 + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(3S)-3''-hydroxy-L-isoleucine + 2-oxoglutarate + O2 <=> (3S,4R)-3'',4-dihydroxy-L-isoleucine + succinate + CO2 1.14.11.75 31-hydroxy-L-isoleucine 4-dioxygenase

L-valine + 2-oxoglutarate + O2 <=> 4-hydroxy-L-valine + succinate + CO2 1.14.11.74 L-isoleucine 31-dioxygenase

thymine + 2-oxoglutarate + 2 O2 <=> Uracil-5-carboxylate + succinate + CO2 + H2O 1.14.11.6 thymine dioxygenase

Procollagen + 2-oxoglutarate + O2 <=> procollagen_trans-3-hydroxy-L-proline + succinate + CO2 1.14.11.7 procollagen-proline 3-dioxygenase

thymidine + 2-oxoglutarate + O2 <=> 5-methyluridine + succinate + CO2 1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase

Leucocyanidin + 2-oxoglutarate + O2 <=> cis-dihydroquercetin + taxifolin + succinate + CO2 1.14.20.4 anthocyanidin synthase

D-carnitine + 2-oxoglutarate + O2 <=> 3-dehydrocarnitine + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

L-carnitine + 2-oxoglutarate + O2 <=> 3-dehydrocarnitine + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

uridine + 2-oxoglutarate + O2 <=> D-ribono-1,5-lactone + Uracil + succinate + CO2 1.14.11.10 pyrimidine-deoxynucleoside 1'-dioxygenase

2''-deoxy-2''-fluorouridine + 2-oxoglutarate + O2 <=> Uracil + 2-fluororibonolactone + succinate + CO2 1.14.11.10 pyrimidine-deoxynucleoside 1'-dioxygenase

5-(2-hydroxyethyl)uracil + 2-oxoglutarate + O2 <=> 5-(1,2-Dihydroxyethyl)uracil + succinate + CO2 1.14.11.6 thymine dioxygenase

5-Vinyluracil + 2-oxoglutarate + O2 <=> 5-(1,2-Dihydroxyethyl)uracil + succinate + CO2 1.14.11.6 thymine dioxygenase

5-bromodeoxyuridine + 2-oxoglutarate + O2 <=> 5-Bromouridine + succinate + CO2 1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase

penicillin_G + 2-oxoglutarate + O2 <=> 7-phenylacetamidodeacetoxycephalosporanic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

homoeriodictyol + 2-oxoglutarate + O2 <=> 5,7,4''-trihydroxy-3''-methoxyflavone + succinate + CO2 + H2O 1.14.20.5 flavone synthase I

thymidine + 2-oxoglutarate + O2 <=> 5-hydroxymethyluridine + succinate + CO2 1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase

5-Hydroxymethyldeoxyuridine + 2-oxoglutarate + O2 <=> 5-hydroxymethyluridine + succinate + CO2 1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase

beta-carotene + 2-oxoglutarate + O2 + H2O <=> canthaxanthin + succinate + CO2 + 4 H+ 1.14.11.B16

gibberellin_a4 + 2-oxoglutarate + O2 <=> gibberellin_34 + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

3''-methylcephem + 2-oxoglutarate + O2 <=> 3''-hydroxymethylcephem + succinate + CO2 1.14.11.26 deacetoxycephalosporin-C hydroxylase

(2S,3R)-proclavaminate + 2-oxoglutarate + O2 <=> clavaminate + succinate + CO2 + H2O 1.14.11.21 clavaminate synthase

4-Dimethylaminobutyric_acid + 2-oxoglutarate + O2 <=> DL-norcarnitine + succinate + CO2 1.14.11.1 gamma-butyrobetaine dioxygenase

S-ethyl-L-cysteine + 2-oxoglutarate + O2 <=> S-ethyl-L-Cys_sulfoxide + succinate + CO2 1.14.11.45 L-isoleucine 4-hydroxylase

naringenin + 2-oxoglutarate + O2 <=> dihydrokaempferol + kaempferol + succinate + CO2 + H2O 1.14.20.6 flavonol synthase

naringenin + 2-oxoglutarate + O2 <=> (2R,3S)-cis-dihydrokaempferol + (2S,3S)-dihydrokaempferol + kaempferol + succinate + CO2 + H2O 1.14.20.6 flavonol synthase

naringenin + 2-oxoglutarate + O2 <=> (2R,3S)-cis-dihydrokaempferol + (+)-dihydrokaempferol + apigenin + kaempferol + succinate + CO2 + H2O 1.14.20.6 flavonol synthase

naringenin + 2-oxoglutarate + O2 <=> kaempferol + succinate + CO2 + H2O 1.14.20.6 flavonol synthase

cis-dihydrokaempferol + 2-oxoglutarate + O2 <=> kaempferol + succinate + CO2 + H2O 1.14.20.5 flavone synthase I
1.14.20.6 flavonol synthase


2-oxoglutarate + O2 + ascorbate <=> succinate + CO2 + dehydroascorbate + H2O 1.14.11.2 procollagen-proline 4-dioxygenase
1.14.11.4 procollagen-lysine 5-dioxygenase


eriodictyol + 2-oxoglutarate + O2 <=> dihydroquercetin + luteolin + succinate + CO2 + 2 H2O 1.14.20.4 anthocyanidin synthase

2R,3S,4S-cis-leucoanthocyanidin + 2-oxoglutarate + O2 <=> luteolin + succinate + CO2 + 2 H2O 1.14.20.4 anthocyanidin synthase

poly(L-Pro) + 2-oxoglutarate + O2 <=> poly_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

poly_L-proline + 2-oxoglutarate + O2 <=> poly_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

L-hyoscyamine + O2 + 2-oxoglutarate + O2 <=> Scopolamine + succinate + CO2 1.14.11.11 hyoscyamine (6S)-dioxygenase

gibberellin_a20 + 2-oxoglutarate + O2 <=> gibberellin + succinate + CO2 1.14.11.15 gibberellin 3beta-dioxygenase

adipyl_6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> 7-aminodeacetoxycephalosporanic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

penicillin_G + 2-oxoglutarate + O2 <=> 7-aminodeacetoxycephalosporanic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

pentanoate + 2-oxoglutarate + O2 <=> 2-hydroxyvalerate + succinate + CO2 1.14.11.17 taurine dioxygenase

3-exomethylenecephalosporin + 2-oxoglutarate + O2 <=> deacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.11.26 deacetoxycephalosporin-C hydroxylase

3-oxomethylenecephalosporin_C + 2-oxoglutarate + O2 <=> deacetoxycephalosporin_C + succinate + CO2 1.14.11.26 deacetoxycephalosporin-C hydroxylase

naringenin + 2-oxoglutarate + O2 <=> apigenin + (+)-dihydrokaempferol + succinate + CO2 + 2 H2O 1.14.20.4 anthocyanidin synthase

naringenin + 2-oxoglutarate + O2 <=> apigenin + 2-hydroxynaringenin + succinate + CO2 + H2O 1.14.20.5 flavone synthase I

(2R)-naringenin + 2-oxoglutarate + O2 <=> apigenin + succinate + CO2 + H2O 1.14.20.4 anthocyanidin synthase
1.14.20.5 flavone synthase I


3-exomethylenecephalosporin_C + 2-oxoglutarate + O2 <=> deacetylcephalosporin_C + succinate + CO2 + H2O 1.14.11.26 deacetoxycephalosporin-C hydroxylase
1.14.20.1 deacetoxycephalosporin-C synthase


(Ala-Pro-Gly)5 + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Ala-Thr-Pro-Pro-Pro-Val)3 + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Pro-Ala-Gly)5 + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

Ser-Pro-Pro-Pro-Pro-Val-Ser-Pro-Pro-Pro-Val-Ser-Pro-Pro-Pro-Pro-Val + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

Ser-Pro-Pro-Pro-Val-Tyr-Lys-Ser-Pro-Pro-Pro-Pro-Val-Lys-His-Tyr-Ser-Pro-Pro-Pro-Val + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

Asp-Ala-Leu-Thr-Leu-Leu-Ala-Pro-Ala-Ala-Gly-Asp-Thr-Ile-Ile-Ser-Leu-Phe-Gly + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

Asp-Leu-Asp-Leu-Glu-Met-Leu-Ala-Pro-Tyr-Ile-Pro-Met-Asp-Asp-Asp-Phe-Gln-Leu + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

Arg-Gly-(Pro-Pro-Gly)5 + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

tert-butyloxycarbonyl-Pro-Pro-Ala-Pro-OH + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

tert-butyloxycarbonyl-Pro-Pro-Gln-Pro-OCH3 + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

tert-butyloxycarbonyl-Pro-Pro-Gly-Pro-Pro-OH + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

tert-butyloxycarbonyl-Pro-Pro-Gly-Pro + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Gly-Pro-Ala)n + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

tert-butyloxycarbonyl-Pro-Pro-Gly-Pro-NHCH3 + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Pro-Gly-Pro)n + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Pro-Ala-Pro-Lys)10 + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

Proline_containing_peptide + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Gly-Ala-Pro)n + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Gly-Pro-4Hyp)5 + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

Glu-Gly-(Pro-Pro-Gly)5 + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Pro-Glu-Pro-Pro-Ala)5 + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Ser-Pro-Lys-Pro-Pro)5 + 2-oxoglutarate + O2 <=> 4-hydroxyproline_containing_peptide + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

gibberellin + 2-oxoglutarate + O2 <=> 2beta-hydroxygibberellin + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

hypoxia-inducible_factor-L-asparagine + 2-oxoglutarate + O2 <=> hypoxia-inducible_factor-(3S)-3-hydroxy-L-asparagine + succinate + CO2 1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase

DLDLEMLAPYIPMDDDFQL + 2-oxoglutarate + O2 <=> DLDLEMLA-((4R)-4-hydroxy-L-proline)-YIPMDDDFQL + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

butyryl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxybutanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

zeaxanthin + 2-oxoglutarate + O2 + H2O <=> astaxanthin + succinate + CO2 + 4 H+ 1.14.11.B16

S-(L-glutamyl)-[peptidyl-carrier_protein_of_nonribosomal_peptide_synthetase_KtzH] + 2-oxoglutarate + O2 <=> S-(erythro-3-hydroxy-L-glutamyl)-[peptidyl-carrier-protein_of_nonribosomal_peptide_synthetase_KtzH] + succinate + CO2 1.14.11.B15

S-(L-glutamyl)-[peptidyl-carrier_protein_of_nonribosomal_peptide_synthetase_KtzH] + 2-oxoglutarate + O2 <=> S-(threo-3-hydroxy-L-glutamyl)-[peptidyl-carrier-protein_of_nonribosomal_peptide_synthetase_KtzH] + succinate + CO2 1.14.11.B17

Collagen + 2-oxoglutarate + O2 <=> 5-hydroxylysyl-collagen + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

lysine_hydroxylated_protocollagen + 2-oxoglutarate + O2 <=> lysine_4-hydroxyproline_containing_protocollagen + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

[protein]-L-asparagine + 2-oxoglutarate + O2 <=> peptide_3-hydroxy-L-asparagine + succinate + CO2 1.14.11.16 peptide-aspartate beta-dioxygenase

(+/-)-1-deoxypentalenic_acid + O2 <=> 1-deoxy-11beta-hydroxypentalenic_acid + succinate + CO2 1.14.11.35 1-deoxypentalenic acid 11beta-hydroxylase

7-(3-amino-3-carboxypropyl)wyosine37_in_tRNAPhe + 2-oxoglutarate + O2 <=> 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine37_in_tRNAPhe + succinate + CO2 1.14.11.42 tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase

100-amino_acid_alpha1(I)_collagen_fragment_L-proline + 2-oxoglutarate + O2 <=> 100-amino_acid_alpha1(I)_collagen_fragment_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

510-amino_acid_alpha1(I)_collagen_fragment_L-proline + 2-oxoglutarate + O2 <=> 510-amino_acid_alpha1(I)_collagen_fragment_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

HIF_(L-Asn803) + 2-oxoglutarate + O2 <=> HIF_(3-hydroxy-L-Asn803) + succinate + CO2 1.14.11.16 peptide-aspartate beta-dioxygenase

HIF-1alpha_peptide_Asp788-Leu822_(L-Asn803) + 2-oxoglutarate + O2 <=> HIF-1alpha_peptide_Asp788-Leu822_(3-hydroxy-L-Asn803) + succinate + CO2 1.14.11.16 peptide-aspartate beta-dioxygenase

2-Hydroxy-3-phenylpropionyltropine + 2-oxoglutarate + O2 <=> 2-Hydroxy-3-phenylpropionyl-6-hydroxytropine + succinate + CO2 1.14.11.11 hyoscyamine (6S)-dioxygenase

3-Hydroxy-3-phenylpropionyltropine + 2-oxoglutarate + O2 <=> 3-Hydroxy-3-phenylpropionyl-6-hydroxytropine + succinate + CO2 1.14.11.11 hyoscyamine (6S)-dioxygenase
1.14.20.13 6beta-hydroxyhyoscyamine epoxidase


Apoatropine + 2-oxoglutarate + O2 <=> 6-Hydroxyapoatropine + succinate + CO2 1.14.11.11 hyoscyamine (6S)-dioxygenase
1.14.20.13 6beta-hydroxyhyoscyamine epoxidase


L-Homatropine + 2-oxoglutarate + O2 <=> 6-Hydroxyhomatropine + succinate + CO2 1.14.11.11 hyoscyamine (6S)-dioxygenase
1.14.20.13 6beta-hydroxyhyoscyamine epoxidase


norhyoscyamine + 2-oxoglutarate + O2 <=> 6-Hydroxynorhyoscyamine + succinate + CO2 + H2O 1.14.20.13 6beta-hydroxyhyoscyamine epoxidase

L-Norhyoscyamine + 2-oxoglutarate + O2 <=> 6-Hydroxynorhyoscyamine + succinate + CO2 1.14.11.11 hyoscyamine (6S)-dioxygenase

Phenylacetyltropine + 2-oxoglutarate + O2 <=> 6-Hydroxyphenylacetyltropine + succinate + CO2 1.14.11.11 hyoscyamine (6S)-dioxygenase
1.14.20.13 6beta-hydroxyhyoscyamine epoxidase


gibberellin_a4 + 2-oxoglutarate + O2 <=> gibberellin_a4 + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

(L-Pro-L-Glu-L-Pro-L-Pro-L-Ala)5_L-proline + 2-oxoglutarate + O2 <=> (L-Pro-L-Glu-L-Pro-L-Pro-L-Ala)5_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(L-Pro-L-Pro-Gly)10_L-proline + 2-oxoglutarate + O2 <=> (L-Pro-L-Pro-Gly)10-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(L-Ser-L-Pro)19_L-proline + 2-oxoglutarate + O2 <=> (L-Ser-L-Pro)19_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(L-Ser-L-Pro-L-Ala-L-Pro-L-Pro)5_L-proline + 2-oxoglutarate + O2 <=> (L-Ser-L-Pro-L-Ala-L-Pro-L-Pro)5_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(L-Ser-L-Pro-L-Glu-L-Pro-L-Pro)5_L-proline + 2-oxoglutarate + O2 <=> (L-Ser-L-Pro-L-Glu-L-Pro-L-Pro)5_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(L-Ser-L-Pro-L-Lys-L-Pro-L-Pro)5_L-proline + 2-oxoglutarate + O2 <=> (L-Ser-L-Pro-L-Lys-L-Pro-L-Pro)5_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

ankyrin_repeat_domain_of_endogenous_Notch_receptor_L-asparagine + 2-oxoglutarate + O2 <=> ankyrin_repeat_domain_of_endogenous_Notch_receptor_3-hydroxy-L-asparagine + succinate + CO2 1.14.11.16 peptide-aspartate beta-dioxygenase

hypoxia-induced_factor_alpha_oxygen-dependent_degradation_domain_L-proline + 2-oxoglutarate + O2 <=> hypoxia-induced_factor_alpha_oxygen-dependent_degradation_domain_L-4-hydroxyproline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

L-lysine-[collagen] + 2-oxoglutarate + O2 <=> 5-hydroxy-L-lysine-[collagen] + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

L-lysine-[U2AF65] + 2-oxoglutarate + O2 <=> 5-hydroxy-L-lysine-[U2AF65] + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

Argonaute_protein + 2-oxoglutarate + O2 <=> 4-hydroxyproline-Argonaute_protein + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Pro-Pro-Gly)n + 2-oxoglutarate + O2 <=> (Pro-4-hydroxy-Pro-Gly)n + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

Collagen + 2-oxoglutarate + O2 <=> 4-Hydroxyproline_containing_collagen + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

Protocollagen + 2-oxoglutarate + O2 <=> 4-Hydroxyproline_containing_collagen + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

protein + 2-oxoglutarate + O2 <=> Hydroxylysine-rich_peptides + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

poly(L-Pro) + 2-oxoglutarate + O2 <=> Poly(4-hydroxyproline) + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

hypoxia-inducible_factor-L-proline + 2-oxoglutarate + O2 <=> hypoxia-inducible_factor-(3S)-3-hydroxy-proline + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

hypoxia-inducible_factor-L-proline + 2-oxoglutarate + O2 <=> hypoxia-inducible_factor1alpha_N-terminal_oxygen-dependent_degradation_domain-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase

hypoxia-inducible_factor-L-proline + 2-oxoglutarate + O2 <=> hypoxia-inducible_factor1alpha_N-terminal_oxygen-dependent_degradation_domain-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

hypoxia-inducible_factor2alpha_C-terminal_oxygen-dependent_degradation_domain-L-proline + 2-oxoglutarate + O2 <=> hypoxia-inducible_factor2alpha_C-terminal_oxygen-dependent_degradation_domain-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase
1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase


hypoxia-inducible_factor2alpha_C-terminal_oxygen-dependent_degradation_domain-L-proline + 2-oxoglutarate + O2 <=> hypoxia-inducible_factor2alpha_C-terminal_oxygen-dependent_degradation_domain-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

hypoxia-inducible_factor2alpha_N-terminal_oxygen_dependent_degradation_domain-L-proline + 2-oxoglutarate + O2 <=> hypoxia-inducible_factor2alpha_N-terminal_oxygen_dependent_degradation_domain-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase
1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase


rabankyrin-5 + 2-oxoglutarate + O2 <=> trihydroxy-rabankyrin-5 + succinate + CO2 1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase

3-methylhexadecanoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxy-3-methylhexadecanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

[50S_ribosomal_protein_L16]-L-Arg81 + 2-oxoglutarate + O2 <=> [50S_ribosomal_protein_L16]-(3R)-3-hydroxy-L-Arg81 + succinate + CO2 1.14.11.47 [50S ribosomal protein L16]-arginine 3-hydroxylase

phytanoyl-CoA + 2-oxoglutarate + O2 <=> alpha-hydroxyphytanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

(Ile-Lys-Gly)3 + 2-oxoglutarate + O2 <=> (Ile-5-hydroxylyseine-Gly)3 + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

(Pro-Pro-Gly)4-Ala-Arg-Gly-Met-Lys-Gly-His-Arg-Gly-(Pro-Pro-Gly)4 + 2-oxoglutarate + O2 <=> (Pro-Pro-Gly)4-Ala-Arg-Gly-Met-5-hydroxylysine-Gly-His-Arg-Gly-(Pro-Pro-Gly)4 + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

Dihydrothymine + 2-oxoglutarate + O2 <=> 5,6-dihydro-5-(hydroxymethyl)uracil + succinate + CO2 1.14.11.6 thymine dioxygenase

5-Ethynyluracil + 2-oxoglutarate + O2 + H2O <=> 5-(carboxymethyl)uracil + succinate + CO2 1.14.11.6 thymine dioxygenase

5-(methylthio)uracil + 2-oxoglutarate + O2 <=> 5-(methylsulfonyl)uracil + 5-(methylsulfinyl)uracil + succinate + CO2 1.14.11.6 thymine dioxygenase

6-Azathymidine + 2-oxoglutarate + O2 <=> 5-mehyluridine + succinate + CO2 1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase

dTMP + 2-oxoglutarate + O2 <=> 5-methyluridine_5''-phosphate + succinate + CO2 1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase

Ala-Arg-Gly-Ile-Lys-Gly-Ile-Arg-Gly-Phe-Ser-Gly + 2-oxoglutarate + O2 <=> Ala-Arg-Gly-Ile-5-hydroxylysine-Gly-Ile-Arg-Gly-Phe-Ser-Gly + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

Ala-Arg-Gly-Met-Lys-Gly-His-Arg-Gly-(Pro-Pro-Gly)4 + 2-oxoglutarate + O2 <=> Ala-Arg-Gly-Met-5-hydroxylysine-Gly-His-Arg-Gly-(Pro-Pro-Gly)4 + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

gibberellin_a20 + 2-oxoglutarate + O2 <=> gibberellin_29 + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

gibberellin_a9 + 2-oxoglutarate + O2 <=> gibberellin_51 + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

gibberellin_44 + 2-oxoglutarate + O2 <=> gibberellin_a38 + succinate + CO2 1.14.11.15 gibberellin 3beta-dioxygenase

Gly-Val-Pro-Gly-Val + 2-oxoglutarate + O2 <=> Gly-Val-4-hydroxyproline-Gly-Val + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

Lys-Pro-Ala + 2-oxoglutarate + O2 <=> Lys-4-hydroxyproline-Ala + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

Butyrate + 2-oxoglutarate + O2 <=> 2-hydroxy-4-butyric_acid + succinate + CO2 1.14.11.17 taurine dioxygenase

4-aminobutanoate + 2-oxoglutarate + O2 <=> D-2-hydroxy-4-aminobutyric_acid + succinate + CO2 1.14.11.17 taurine dioxygenase

5-Aminopentanoate + 2-oxoglutarate + O2 <=> D-2-hydroxy-5-aminovaleric_acid + succinate + CO2 1.14.11.17 taurine dioxygenase

6-aminohexanoate + 2-oxoglutarate + O2 <=> D-2-hydroxy-6-aminocaproic_acid + succinate + CO2 1.14.11.17 taurine dioxygenase

beta-Alanine + 2-oxoglutarate + O2 <=> D-isoserine + succinate + CO2 1.14.11.17 taurine dioxygenase

DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN + 2-oxoglutarate + O2 <=> DESGLPQLTSYDAEV-(3S)-3-hydroxy-L-asparaginyl-APIQGSRNLLQGEELLRALDQVN + succinate + CO2 1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase

2-oxoglutarate + trans-cinnamoyltropine + O2 <=> succinate + trans-cinnamoyl-6-hydroxytropine + CO2 1.14.11.11 hyoscyamine (6S)-dioxygenase

hypoxia-inducible_factor_1_alpha-L-proline + 2-oxoglutarate + O2 <=> hypoxia-inducible_factor_1alpha-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

hypoxia-inducible_factor_1alpha-L-proline + 2-oxoglutarate + O2 <=> hypoxia-inducible_factor_1alpha-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

adiponectin-L-lysine + 2-oxoglutarate + O2 <=> adiponectin-5-hydroxy-L-lysine + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

human_procollagen-like_(P-P-G)10_peptide_L-proline + 2-oxoglutarate + O2 <=> human_procollagen-like_(P-P-G)10_peptide_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

human_procollagen-like_(P-P-G)5_peptide_L-proline + 2-oxoglutarate + O2 <=> human_procollagen-like_(P-P-G)5_peptide_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

L-threonyl-[L-threonyl-carrier_protein_SyrB1] + 2-oxoglutarate + O2 + 2 Cl- <=> 4,4-dichloro-L-threonyl-[L-threonyl-carrier_protein_SyrB1] + succinate + CO2 + H2O 1.14.20.15 L-threonyl-[L-threonyl-carrier protein] 4-chlorinase

L-threonyl-[L-threonyl-carrier_protein_SyrB1] + 2-oxoglutarate + O2 + Br- <=> 4-bromo-L-threonyl-[L-threonyl-carrier_protein_SyrB1] + succinate + CO2 + H2O 1.14.20.15 L-threonyl-[L-threonyl-carrier protein] 4-chlorinase

L-threonyl-[L-threonyl-carrier_protein_SyrB1] + 2-oxoglutarate + O2 + Cl- <=> 4-chloro-L-threonyl-[L-threonyl-carrier_protein_SyrB1] + succinate + CO2 + H2O 1.14.20.15 L-threonyl-[L-threonyl-carrier protein] 4-chlorinase

acetyl-L-Arg + 2-oxoglutarate + O2 <=> 4-hydroxy-N-alpha-acetyl-L-arginine + succinate + CO2 + H2O 1.14.11.21 clavaminate synthase

deoxyamidinoproclavaminate + 2-oxoglutarate + O2 <=> E-(2S)-5-amino-2(2''-oxoazetidin-1-yl)-pent-3,4-enoate + succinate + CO2 + H2O 1.14.11.21 clavaminate synthase

(L-Pro-L-Ala-L-Pro-L-Lys)2 + 2-oxoglutarate + O2 <=> (L-Pro-L-Ala-L-Pro-L-Lys)2-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(L-Pro-L-Ala-L-Pro-L-Lys)3 + 2-oxoglutarate + O2 <=> (L-Pro-L-Ala-L-Pro-L-Lys)3-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(L-Pro-L-Pro-Gly)10 + 2-oxoglutarate + O2 <=> (L-Pro-L-Pro-Gly)10-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(L-Pro-L-Pro-Gly)2 + 2-oxoglutarate + O2 <=> (L-Pro-L-Pro-Gly)2-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(L-Pro-L-Pro-Gly)5 + 2-oxoglutarate + O2 <=> (L-Pro-L-Pro-Gly)5-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

5,6-dihydroxythymine + 2-oxoglutarate + O2 <=> 5,6-dihydroxy-5-(hydroxymethyl)uracil + succinate + CO2 1.14.11.6 thymine dioxygenase

carboxymethylated_collagen_L-proline + 2-oxoglutarate + O2 <=> carboxymethylated_collagen-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

first_epidermal_growth_factor-like_domain-L-aspartate + 2-oxoglutarate + O2 <=> first_epidermal_growth_factor-like_domain-3-hydroxy-L-aspartate + succinate + CO2 1.14.11.16 peptide-aspartate beta-dioxygenase

L-Pro-L-Ala-L-Pro-L-Lys + 2-oxoglutarate + O2 <=> L-Pro-L-Ala-L-Pro-L-Lys-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

L-Pro-L-Pro-Gly + 2-oxoglutarate + O2 <=> L-Pro-L-Pro-Gly-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

peptidyl_L-proline + 2-oxoglutarate + O2 <=> peptidyl-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

protocollagen_type_I_L-proline + 2-oxoglutarate + O2 <=> protocollagen_type_I-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

protocollagen_type_I_L-proline+_2-oxoglutarate + O2 <=> protocollagen_type_I-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

tert-butyloxycarbonyl-L-Pro-L-Pro-Gly + 2-oxoglutarate + O2 <=> tert-butyloxycarbonyl-L-Pro-L-Pro-Gly-trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

[RCCD1]-L-arginine + 2-oxoglutarate + O2 <=> [RCCD1]-(3R)-3-hydroxy-L-arginine + succinate + CO2 1.14.11.73 [protein]-arginine 3-hydroxylase

[RPS6]-L-arginine + 2-oxoglutarate + O2 <=> [RPS6]-(3R)-3-hydroxy-L-arginine + succinate + CO2 1.14.11.73 [protein]-arginine 3-hydroxylase

isoliquiritigenin + 2-oxoglutarate + O2 <=> butein + succinate + CO2 1.14.11.B18

ampicillin + 4-methyl-2-oxopentanoate + O2 <=> cephalexin + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

decanoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxydecanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

(2R)-naringenin + 2-oxoglutarate + O2 <=> cis-dihydrokaempferol + succinate + CO2 + H2O 1.14.20.6 flavonol synthase

adipyl_6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> (6R,7R)-7-[(5-carboxypentanoyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

N-adipyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> (6R,7R)-7-[(5-carboxypentanoyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

gibberellin_12 + 2-oxoglutarate + O2 <=> gibberellin_110 + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

gibberellin_53 + 2-oxoglutarate + O2 <=> gibberellin_97 + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

hypoxia-inducible_transcription_factor + 2-oxoglutarate + O2 <=> hypoxia-inducible_transcription_factor_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(ATPPPV)3 + 2-oxoglutarate + O2 <=> trans-4-hydroxy-L-proline_(ATPPPV)3 + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Pro-Pro-Gly)10 + 2-oxoglutarate + O2 <=> trans-4-hydroxy-L-proline_(Pro-Pro-Gly)10 + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Pro-Pro-Gly)10_L-proline + 2-oxoglutarate + O2 <=> trans-4-hydroxy-L-proline_(Pro-Pro-Gly)10 + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

(Pro-Pro-Gly)2_L-proline + 2-oxoglutarate + O2 <=> (Pro-Pro-Gly)2_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

citronellyl-CoA + 2-oxoglutarate + O2 <=> 3,7-dimethyl-2-hydroxyocta-7-enoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

3-ethylnonanoyl-CoA + 2-oxoglutarate + O2 <=> 3-ethoxy-2-hydroxyhexadecanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

3-methyl-5-phenyl-pentanoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxy-3-methyl-5-phenylpentanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

3-methyldodecanoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxy-3-methyldodecanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

3-methylheptanoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxy-3-methylheptanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

3-methylnonanoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxy-3-methylnonanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

3-methylundecanoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxy-3-methylundecanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

dansyl-Gly-Phe-Pro-Gly-OEt + 2-oxoglutarate + O2 <=> dansyl-Gly-Phe-trans-4-hydroxy-L-proline-Gly-OEt + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

DLDLEMLAPAIPMDDDFQLRSFDQ + 2-oxoglutarate + O2 <=> DLDLEMLAPAIPMDDDFQLRSFDQ_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

DLDLEMLAPGIPMDDDFQL + 2-oxoglutarate + O2 <=> DLDLEMLAPGIPMDDDFQL_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

DLDLEMLAPYIPMD + 2-oxoglutarate + O2 <=> DLDLEMLAPYIPMD_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

DLDLEMLAPYIPMDD + 2-oxoglutarate + O2 <=> DLDLEMLAPYIPMDD_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

DLDLEMLAPYIPMDDDF + 2-oxoglutarate + O2 <=> DLDLEMLAPYIPMDDDF_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

DLDLEMLAPYIPMDDDFQL + 2-oxoglutarate + O2 <=> DLDLEMLAPYIPMDDDFQL_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

DLDLEMLAPYIPMDDDFQLRSFDQ + 2-oxoglutarate + O2 <=> DLDLEMLAPYIPMDDDFQLRSFDQ_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

lauroyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxydodecanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

EMLAPYIPMDDDFQL + 2-oxoglutarate + O2 <=> EMLAPYIPMDDDFQL_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

hesperetin + 2-oxoglutarate + O2 <=> 3,5-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-chromen-4-one + succinate + CO2 + H2O 1.14.20.5 flavone synthase I

palmitoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxyhexadecanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

hexanoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxyhexanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

L-lysine_containing_nonapeptides + 2-oxoglutarate + O2 <=> 5-hydroxy-L-lysine_containing_nonapeptides + succinate + CO2 1.14.11.4 procollagen-lysine 5-dioxygenase

LAPYIPMDDDFQL + 2-oxoglutarate + O2 <=> LAPYIPMDDDFQL_trans-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

stearoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxyoctadecanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

octanoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxyoctanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

pinocembrin + 2-oxoglutarate + O2 <=> 5-acetoxy-7-hydroxyflavone + succinate + CO2 + H2O 1.14.20.5 flavone synthase I

SPPPPVSPPPVSPPPPV + 2-oxoglutarate + O2 <=> trans-4-hydroxy-L-proline_SPPPPVSPPPVSPPPPV + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

SPPPPVYKSPPPPVKHYSPPPV + 2-oxoglutarate + O2 <=> trans-4-hydroxy-L-proline_SPPPPVYKSPPPPVKHYSPPPV + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

myristoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxytetradecanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

catechin + 2-oxoglutarate + O2 <=> cyanidin + succinate + CO2 + 2 H2O 1.14.20.4 anthocyanidin synthase

(2R,3S,4R)-leucocyanidin + 2-oxoglutarate + O2 <=> cyanidin + succinate + CO2 + 2 H2O 1.14.20.4 anthocyanidin synthase

tert-butyloxycarbonyl-Val-Pro-Gly-Val-OH + 2-oxoglutarate + O2 <=> tert-butyloxycarbonyl-Val-Hyp-Gly-Val-OH + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

tert-butyloxycarbonyl-Gly-Val-Pro-Gly-Val-OH + 2-oxoglutarate + O2 <=> tert-butyloxycarbonyl-Gly-Val-Hyp-Gly-Val-OH + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

7-aminodeacetoxycephalosporanic_acid + 2-oxoglutarate + O2 <=> 7-aminodeacetylcephalosporin + succinate + CO2 1.14.11.26 deacetoxycephalosporin-C hydroxylase

phenylacetyl-7-aminodeacetoxycephalosporanic_acid + 2-oxoglutarate + O2 <=> phenylacetyl-7-aminodeacetylcephalosporin + succinate + CO2 1.14.11.26 deacetoxycephalosporin-C hydroxylase

3,4-dehydro-DL-proline + 2-oxoglutarate + O2 <=> cis-3,4-epoxy-L-proline + succinate + CO2 1.14.11.28 proline 3-hydroxylase

L-azetidine-2-carboxylic_acid + 2-oxoglutarate + O2 <=> cis-3-hydroxyazetidine-L-2-carboxylic_acid + succinate + CO2 1.14.11.28 proline 3-hydroxylase

L-pipecolic_acid + 2-oxoglutarate + O2 <=> cis-5-hydroxypipecolate + cis-3-hydroxy-L-pipecolic_acid + succinate + CO2 1.14.11.56 L-proline cis-4-hydroxylase

L-pipecolic_acid + 2-oxoglutarate + O2 <=> cis-5-hydroxy-L-pipecolic_acid + cis-3-hydroxy-L-pipecolic_acid + succinate + CO2 1.14.11.56 L-proline cis-4-hydroxylase

L-pipecolic_acid + 2-oxoglutarate + O2 <=> cis-3-hydroxy-L-pipecolic_acid + succinate + CO2 1.14.11.28 proline 3-hydroxylase

1-ethyladenine + O2 + 2-oxoglutarate <=> adenine + CO2 + acetaldehyde + succinate + H+ 1.14.11.33 DNA oxidative demethylase

DNA-1-ethyladenine + 2-oxoglutarate + O2 <=> DNA_adenine + acetaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

taurine + 2-oxoglutarate + O2 <=> succinate + CO2 + ethanolamine + sulfite 1.14.11.17 taurine dioxygenase

butanesulfonic_acid + 2-oxoglutarate + O2 <=> sulfite + Butyraldehyde + succinate + CO2 1.14.11.17 taurine dioxygenase

hexanesulfonic_acid + 2-oxoglutarate + O2 <=> sulfite + hexanal + succinate + CO2 1.14.11.17 taurine dioxygenase

1-hexyl_sulfate + 2-oxoglutarate + O2 <=> hexanal + sulfite + succinate + CO2 1.14.11.17 taurine dioxygenase

N-methyltaurine + 2-oxoglutarate + O2 <=> CO2 + succinate + sulfite + methylaminoacetaldehyde 1.14.11.17 taurine dioxygenase

16,17-dihydro_gibberellin_4 + 2-oxoglutarate + O2 <=> 16,17-dihydro_gibberellin_34 + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

penicillin_F + 2-oxoglutarate + O2 <=> 7-((3E)-hex-3-enoyl)aminocephalosporanic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

gibberellin_a20 + 2-oxoglutarate + O2 <=> 2beta-hydroxygibberellin_20 + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

methyl_gibberellin_A4 + 2-oxoglutarate + O2 <=> gibberellin_34_methyl-ester + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

gibberellin_a9 + 2-oxoglutarate + O2 <=> 2beta-hydroxygibberellin_9 + succinate + CO2 1.14.11.13 gibberellin 2beta-dioxygenase

S-methyl-L-cysteine + 2-oxoglutarate + O2 <=> methiin + succinate + CO2 1.14.11.45 L-isoleucine 4-hydroxylase

penicillin_X + 2-oxoglutarate + O2 <=> 7-[(4-hydroxyphenyl)acetyl]aminocephalosporanic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

penicillin_mX + 2-oxoglutarate + O2 <=> 7-[(3-hydroxyphenyl)acetyl]aminocephalosporanic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

poly(ethylene_glycol)-Gly-L-Tyr-L-Pro-Gly-OCH2CH2OH + 2-oxoglutarate + O2 <=> poly(ethylene_glycol)-Gly-L-Tyr-L-(2S,4R)-4-hydroxy-Pro-Gly-OCH2CH2OH + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

propionate + 2-oxoglutarate + O2 <=> Lactate + succinate + CO2 1.14.11.17 taurine dioxygenase

N-((thiophen-2-yl)acetyl)-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N-[(5R,6R)-3,3-dimethyl-2,7-dioxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-(thiophen-2-yl)acetamide + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

butyryl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> 7-butyrylaminocephalosporanic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

heptanoyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> 7-heptanoylaminodesacetoxycephalosporanic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

hexanoyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> 7-hexanoylaminodesacetoxycephalosporanic_acid + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

N-nonanoyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N7-nonanoyldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

N-octanoyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N7-octanoyldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

Procollagen_L-proline + 2-oxoglutarate + O2 <=> procollagen_trans-(2S,4R)-4-hydroxy-L-proline + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase

N-valeryl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N7-pentanoyldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

DALDLEMLAPYISMDDDFQL + 2-oxoglutarate + O2 <=> DALDLEMLA-((4R)-4-hydroxy-L-proline)-YISMDDDFQL + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

DALTLLAPAAGDTIISLFG + 2-oxoglutarate + O2 <=> DALTLLA-((4R)-4-hydroxy-L-proline)-AAGDTIISLFG + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase
1.14.11.29 hypoxia-inducible factor-proline dioxygenase


DLDLEMLAPAIPMDDDFQL + 2-oxoglutarate + O2 <=> DLDLEMLA-((4R)-4-hydroxy-L-proline)-AIPMDDDFQL + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase
1.14.11.29 hypoxia-inducible factor-proline dioxygenase


DLDLEMLAPGIPMDDDFQL + 2-oxoglutarate + O2 <=> DLDLEMLA-((4R)-4-hydroxy-L-proline)-GIPMDDDFQL + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

DLDLEMLAPYIPMD + 2-oxoglutarate + O2 <=> DLDLEMLA-((4R)-4-hydroxy-L-proline)-YIPMD + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

DLDLEMLAPYIPMDD + 2-oxoglutarate + O2 <=> DLDLEMLA-((4R)-4-hydroxy-L-proline)-YIPMDD + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

DLDLEMLAPYIPMDDDF + 2-oxoglutarate + O2 <=> DLDLEMLA-((4R)-4-hydroxy-L-proline)-YIPMDDDF + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

DLDLEMLAPYIPMDDDFQLRSFDQ + 2-oxoglutarate + O2 <=> DLDLEMLA-((4R)-4-hydroxy-L-proline)-YIPMDDDFQLRSFDQ + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

DLEMLAPYIPMDDDFQL + 2-oxoglutarate + O2 <=> DLEMLA-((4R)-4-hydroxy-L-proline)-YIPMDDDFQL + succinate + CO2 1.14.11.2 procollagen-proline 4-dioxygenase
1.14.11.29 hypoxia-inducible factor-proline dioxygenase


ELDLETLAPYIPMDGEDFQ + 2-oxoglutarate + O2 <=> ELDLETLA-((4R)-4-hydroxy-L-proline)-YIPMDGEDFQ + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

EMLAPYIPMDD + 2-oxoglutarate + O2 <=> EMLA-((4R)-4-hydroxy-L-proline)-YIPMDD + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

EMLAPYIPMDDDFQL + 2-oxoglutarate + O2 <=> EMLA-((4R)-4-hydroxy-L-proline)-YIPMDDDFQL + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

LAPYIPMDDDFQL + 2-oxoglutarate + O2 <=> LA-((4R)-4-hydroxy-L-proline)-YIPMDDDFQL + succinate + CO2 1.14.11.29 hypoxia-inducible factor-proline dioxygenase

acetyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N-acetyldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

N-acetyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N-acetyldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

N-adipyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N-adipyldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

butyryl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N-butyryldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

decanoyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N-decanoyldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

heptanoyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N-heptanoyldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

hexanoyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N-hexanoyldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

N-nonanoyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N-nonanoyldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

N-octanoyl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N-octanoyldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

N-valeryl-6-aminopenicillanic_acid + 2-oxoglutarate + O2 <=> N-valeryldeacetoxycephalosporin_C + succinate + CO2 + H2O 1.14.20.1 deacetoxycephalosporin-C synthase

N1-methylthymine + 2-oxoglutarate + O2 <=> N1-methyl-5-hydroxymethyluracil + succinate + CO2 1.14.11.6 thymine dioxygenase

butyrate-4-nitronate + O2 <=> succinate + nitrite + H2O2 1.7.3.5 3-aci-nitropropanoate oxidase

succinate_semialdehyde + H2O + O2 <=> succinate + H2O2 1.17.3.2 xanthine oxidase

pentalenolactone_D + 2 2-oxoglutarate <=> pentalenolactone_F + 2 succinate + 2 CO2 + H2O 1.14.11.36 pentalenolactone F synthase

phytanoyl-CoA + 2-oxoglutarate <=> 2-hydroxyphytanoyl-CoA + succinate + CO2 1.14.11.18 phytanoyl-CoA dioxygenase

(2R,3R:2S,3S)-2-methyl-isocitrate <=> succinate + pyruvate 4.1.3.1 isocitrate lyase

Maleate + NADH <=> succinate + NAD+ 1.3.1.6 fumarate reductase (NADH)

succinate + NAD+ <=> Succinic_anhydride + NADH 1.1.1.48 D-galactose 1-dehydrogenase

O-Succinyl-L-serine + H2O <=> succinate + pyruvate + NH3 2.5.1.48 cystathionine gamma-synthase

fumarate + menaquinol-6 <=> succinate + menaquinone-6 1.3.5.4 fumarate reductase (quinol)

succinyl-CoA + Methylsuccinate <=> succinate + methylsuccinyl-CoA 2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase

succinyl-CoA + 2-methylbutanedioic_aicd <=> methylsuccinyl-CoA + succinate 2.8.3.18 succinyl-CoA:acetate CoA-transferase

triolein + succinate <=> 1,2-dioleoyl-3-succinoylglycerol + 2-oleoyl-1,3-succinoylglycerol 3.1.1.3 triacylglycerol lipase

succinate + ferricyanide <=> fumarate + ferrocyanide 1.3.5.1 succinate dehydrogenase
1.3.5.4 fumarate reductase (quinol)


succinyl-CoA + 2-oxoindole-3-acetate <=> succinate + 2-oxoindole-3-acetyl-CoA 2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase

succinyl-CoA + phenylsuccinate <=> succinate + 2-phenylsuccinyl-CoA + 2-phenylsuccinyl-CoA 2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase

succinyl-CoA + Benzylsuccinic_acid <=> succinate + (R,S)-benzylsuccinyl-CoA 2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase

succinyl-CoA + phenylsuccinate <=> succinate + phenylsuccinyl-CoA 2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase

succinyl-CoA + oxaloacetate <=> oxaloacetyl-CoA + succinate 2.8.3.18 succinyl-CoA:acetate CoA-transferase

Succinylcholine + H2O <=> succinate + choline 3.1.1.8 cholinesterase

succinyldicholine + H2O <=> 2 choline + succinate 3.1.1.7 acetylcholinesterase

succinate + ubiquinone-8 <=> fumarate + ubiquinol-8 1.3.5.1 succinate dehydrogenase

succinate + 2,6-dichlorophenolindophenol <=> fumarate + reduced_2,6-dichlorophenolindophenol 1.3.5.1 succinate dehydrogenase

succinyl-CoA + beta-hydroxybutyrate <=> succinate + 3-hydroxybutyryl-CoA 2.8.3.5 3-oxoacid CoA-transferase

succinate + ubiquinone-2 <=> fumarate + 2,3-dimethoxy-5-methyl-6-geranyl-1,4-benzoquinol 1.3.5.1 succinate dehydrogenase

succinate + 2,3-dimethoxy-5-methyl-1,4-benzoquinone <=> fumarate + reduced_coenzyme_Q0 1.3.5.1 succinate dehydrogenase

succinate + nitroblue_tetrazolium <=> fumarate + 2,3,5-triphenyltetrazolium_chloride 1.3.5.1 succinate dehydrogenase

fumarate + reduced_plumbagin <=> succinate + Plumbagin 1.3.5.1 succinate dehydrogenase

succinate_semialdehyde + 3-acetylpyridine_adenine_dinucleotide + H2O <=> succinate + reduced_acetylpyridine_adenine_dinucleotide + H+ 1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)

O-Succinyl-L-serine + 3,4-dihydroxypyridine <=> L-mimosine + succinate 2.5.1.52 L-mimosine synthase

L-proline + 2-oxoglutarate + O2 <=> trans-L-3-hydroxyproline + succinate 1.14.11.7 procollagen-proline 3-dioxygenase

succinate + menadione <=> fumarate + menadiol 1.3.5.1 succinate dehydrogenase

succinate + phenazine_methosulfate <=> fumarate + phenazine_ethosulfate 1.3.5.1 succinate dehydrogenase

succinate + 2,3-dimethoxy-5-methyl-6-pentyl-1,4-benzoquinone <=> fumarate + 2,3-dimethoxy-5-methyl-6-pentyl-1,4-benzoquinol 1.3.5.1 succinate dehydrogenase

succinate + phenazine_methosulfate <=> fumarate + reduced_phenazine_methosulfate 1.3.5.1 succinate dehydrogenase
1.3.5.4 fumarate reductase (quinol)


succinate + ferrocyanide <=> fumarate + ferricyanide 1.3.5.1 succinate dehydrogenase

(3R)-3-fluoro-4-(trimethylammonio)butanoate + 2-oxoglutarate + O2 <=> 3-dehydrocarnitine + succinate + formylfluoride 1.14.11.1 gamma-butyrobetaine dioxygenase

L-carnitine + 2-oxoglutarate + Ozone <=> 3-dehydrocarnitine + succinate + HCO3- 1.14.11.1 gamma-butyrobetaine dioxygenase

4-ketopimelate + H2O <=> succinate + propionate 3.7.1.2 fumarylacetoacetase

succinate_semialdehyde + H2O + Oxidized_benzyl_viologen <=> succinate + H+ + reduced_benzyl_viologen 1.2.7.5 aldehyde ferredoxin oxidoreductase
1.2.7.B2


succinyl-CoA + fumarate <=> fumaroyl-CoA + succinate 2.8.3.18 succinyl-CoA:acetate CoA-transferase

succinyl-CoA + Maleate <=> succinate + maleyl-CoA 2.8.3.5 3-oxoacid CoA-transferase

fumarate + 2,3-dimethyl-1,4-naphthoquinol <=> succinate + 2,3-dimethyl-1,4-naphthoquinone 1.3.5.1 succinate dehydrogenase
1.3.5.4 fumarate reductase (quinol)


succinyl-CoA + adipate <=> succinate + adipyl-CoA 2.8.3.13 succinate---hydroxymethylglutarate CoA-transferase

N-succinyl-DL-2,6-diaminoheptanedioate + H2O <=> succinate + LL-2,6-Diaminoheptanedioate 3.5.1.18 succinyl-diaminopimelate desuccinylase

succinyl-CoA + 3-oxoglutarate <=> succinate + 3-oxoglutaryl-CoA 2.8.3.6 3-oxoadipate CoA-transferase

fumarate + electron_donor <=> succinate + A 1.3.5.1 succinate dehydrogenase

succinate + 3-azido-2-methyl-5-methoxy-6-geranyl-1,4-benzoquinone <=> fumarate + 3-azido-2-methyl-5-methoxy-6-geranyl-1,4-benzoquinol 1.3.5.1 succinate dehydrogenase

Tripalmitoylglycerol + succinate <=> 1,2-dipalmitoyl-3-succinoylglycerol + 2-palmitoyl-1,3-disuccinoylglycerol 3.1.1.3 triacylglycerol lipase

fumarate + hydroquinone <=> succinate + ubiquinone 1.3.5.1 succinate dehydrogenase

dihydroorotate + fumarate <=> Orotate + succinate 1.3.98.1 dihydroorotate dehydrogenase (fumarate)

fumarate + anthrahydroquinonesulfonate <=> succinate + anthraquinone-2-sulfonate 1.3.5.4 fumarate reductase (quinol)

fumarate + reduced_benzyl_viologen <=> succinate + Oxidized_benzyl_viologen 1.3.1.6 fumarate reductase (NADH)
1.3.5.1 succinate dehydrogenase


O-Succinyl-L-serine + L-homocysteine <=> succinate + L-cystathionine 2.5.1.48 cystathionine gamma-synthase

succinate + oxidized_phenazine_methosulfate <=> fumarate + reduced_phenazine_methosulfate 1.3.5.1 succinate dehydrogenase

succinate + oxidized_N,N,N'',N''-tetramethyl-4-phenylenediamine <=> fumarate + reduced_N,N,N'',N''-tetramethyl-4-phenylenediamine 1.3.5.1 succinate dehydrogenase

succinyl-CoA + methylmalonate <=> succinate + methylmalonyl-CoA 2.8.3.13 succinate---hydroxymethylglutarate CoA-transferase

succinate + 2,3-dimethoxy-5-methyl-6-(3,7-dimethyl-2,6-octadienyl)-1,4-benzoquinone <=> fumarate + 2,3-dimethoxy-5-methyl-6-(3,7-dimethyl-2,6-octadienyl)-1,4-benzoquinol 1.3.5.1 succinate dehydrogenase

succinyl-CoA + malonate <=> succinate + malonyl-CoA 2.8.3.13 succinate---hydroxymethylglutarate CoA-transferase

succinyl-CoA + L-benzylsuccinate <=> succinate + (S)-2-benzylsuccinyl-CoA 2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase

succinyl-CoA + benzylmalonate <=> succinate + benzylmalonyl-CoA 2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase

succinate + oxidized_2,6-dichlorophenolindophenol <=> fumarate + reduced_2,6-dichlorophenolindophenol 1.3.5.1 succinate dehydrogenase

succinate + oxidized_phenazine_ethosulfate <=> fumarate + phenazine_ethosulfate 1.3.5.1 succinate dehydrogenase

succinate + decylubiquinone <=> fumarate + 2,3-Dimethoxy-5-methyl-6-decyl-1,4-benzoquinol 1.3.5.1 succinate dehydrogenase

succinate + decylubiquinone <=> fumarate + decylubiquinol 1.3.5.1 succinate dehydrogenase

succinyl-CoA + 2-oxoadipate <=> succinate + 2-oxoadipyl-CoA 2.8.3.6 3-oxoadipate CoA-transferase

succinate + 4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene_disulfonate <=> fumarate + reduced_WST-1 1.3.5.1 succinate dehydrogenase

succinate + (3S)-citramalyl-CoA <=> succinyl-CoA + citramalate 2.8.3.11 citramalate CoA-transferase

succinate + 1,4-Naphthoquinone <=> fumarate + 1,4-naphthoquinol 1.3.5.1 succinate dehydrogenase

succinyl-CoA + indole-3-acetic_acid <=> succinate + indoleacetyl-CoA 2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase

succinate + duroquinone <=> fumarate + duroquinol 1.3.5.1 succinate dehydrogenase

(1S,2S)-1-hydroxypropane-1,2,3-tricarboxylate <=> succinate + glyoxylate 4.1.3.1 isocitrate lyase

succinate + 2,3-dimethoxy-5-ethyl-6-methyl-1,4-benzoquinone <=> fumarate + 2,3-dimethoxy-5-ethyl-6-methyl-1,4-benzoquinol 1.3.5.1 succinate dehydrogenase

succinate + 2-ethyl-3-methyl-1,4-naphthoquinone <=> fumarate + 2-ethyl-3-methyl-1,4-naphthoquinol 1.3.5.1 succinate dehydrogenase

fumarate + 8-methylmenaquinol-6 <=> succinate + 8-methylmenaquinone-6 1.3.5.4 fumarate reductase (quinol)

H2 + fumarate <=> succinate 1.12.99.6 hydrogenase (acceptor)

succinate <=> tartronate_semialdehyde + CO2 4.1.1.54 dihydroxyfumarate decarboxylase

succinyl-7-aminocephalosporanic_acid + H2O <=> 7-aminocephalosporanic_acid + succinate 3.5.1.93 glutaryl-7-aminocephalosporanic-acid acylase

O-succinyl-L-homoserine + 2-mercaptoethanol <=> L-ethionine + succinate 2.5.1.48 cystathionine gamma-synthase

succinate + NADP+ <=> Succinic_anhydride + NADPH 1.1.1.48 D-galactose 1-dehydrogenase

acetaldehyde + NADP+ + H2O <=> succinate + NADPH + H+ 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]

Succinylmonocholine + H2O <=> succinate + choline 3.1.1.8 cholinesterase

Succinoyl_phosphate + H2O <=> succinate + phosphate 3.6.1.7 acylphosphatase

1-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecyl-glycero-3-phosphocholine + succinate 3.1.1.47 1-alkyl-2-acetylglycerophosphocholine esterase

N1-methyl-ATP + 2-oxoglutarate + O2 <=> ATP + formaldehyde + succinate + CO2 1.14.11.33 DNA oxidative demethylase

O-Succinyl-L-serine + L-cysteine <=> Lanthionine + succinate 2.5.1.48 cystathionine gamma-synthase

O-succinyl-L-homoserine + 3-Mercaptopropionate <=> S-carboxyethyl-L-homocysteine + succinate 2.5.1.48 cystathionine gamma-synthase

O-succinyl-L-homoserine + L-selenocysteine <=> selenocystathionine + succinate 2.5.1.48 cystathionine gamma-synthase

Succinonitrile + H2O <=> succinate + NH3 3.5.5.1 nitrilase
3.5.5.5 arylacetonitrilase
3.5.5.7 aliphatic nitrilase



succinate + electron_acceptor <=> fumarate + reduced_acceptor 1.3.5.1 succinate dehydrogenase

methane + succinate + O2 <=> methanol + fumarate + H2O 1.14.18.3 methane monooxygenase (particulate)

UTP + succinate + CoA <=> ADP + phosphate + succinyl-CoA 6.2.1.5 succinate---CoA ligase (ADP-forming)

O-Succinyl-L-serine + pyrazole <=> 3-(pyrazol-1-yl)-L-alanine + succinate 2.5.1.51 beta-pyrazolylalanine synthase

Succinamide + H2O <=> succinate + NH3 3.5.1.3 omega-amidase
3.5.1.4 amidase


succinyl_phosphate + H2O <=> succinate + phosphate 3.6.1.7 acylphosphatase

succinylthiocholine + H2O <=> thiocholine + succinate 3.1.1.8 cholinesterase

L-aspartate + H2O + fumarate <=> oxaloacetate + NH3 + succinate 1.4.3.16 L-aspartate oxidase

2-methylisocitrate_lactone <=> succinate + pyruvate 4.1.3.30 methylisocitrate lyase

2 acetaldehyde + 3 NAD+ + 4 ATP <=> 3 NADH + succinate + H+ + 4 ADP not assigned

O2 + 2-oxoglutarate + 3-N-Morpholinopropanesulfonic_acid <=> succinate + sulfite + CO2 + 3-(morpholin-4-yl)propanal 1.14.11.17 taurine dioxygenase

2 O-succinyl-L-homoserine + L-cysteine <=> pyruvate + 2 succinate + L-cystathionine + NH3 2.5.1.48 cystathionine gamma-synthase

N-Succinyl-L-isoleucine + H2O <=> succinate + L-isoleucine not assigned

H2O + N2-succinyl-L-arginine <=> succinate + L-arginine not assigned

N-succinyl-L-Ser + H2O <=> L-serine + succinate not assigned

H2O + N-Succinyl-L-valine <=> L-valine + succinate not assigned

H2O + N-succinyl-L-His <=> L-histidine + succinate not assigned

N-Succinyl-L-threonine + H2O <=> succinate + L-threonine not assigned

N-Succinyl-L-Leu + H2O <=> succinate + L-leucine not assigned

N-Succinyl-L-Met + H2O <=> succinate + L-methionine not assigned

ferricyanide + 2-oxoglutarate + H2O <=> CO2 + ferrocyanide + succinate 1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)

Methylsuccinate + H2O <=> succinate + methanol 3.5.1.3 omega-amidase

pyruvate + 3 NAD+ <=> 0 succinate + 3 NADH not assigned

2 succinate + O2 <=> 2 H2O + 2 fumarate not assigned

O2 + FAD + 2-oxoglutarate <=> FADH2 + succinate + H2O + CO2 not assigned

succinyl-CoA + 8-Azaguanosine-5''-diphosphate + phosphate <=> succinate + CoA + 8-Azaguanosine-5''-triphosphate 6.2.1.4 succinate---CoA ligase (GDP-forming)